Overview

High Throughput Screening Market is expected to value over USD 24 billion by 2027 end with a CAGR of over 8% during the forecast period 2020 to 2027.

Growing financial assistance by private and public organizations for research and development activities, advancements in the high throughput screening technology and increased initiatives taken by biotech and pharma companies for promoting this technology are some of the crucial factors contributing to the growth of the market. High throughput screening is primarily used for conducting different chemical, pharmacological and genetic tests that help in the entire process of drug discovery which involves devices for liquid handling, control software, identification of active compounds, biomolecular and genetic interactions. Additionally, this method helps in screening a variety of compounds up to over 10,000 compounds daily and by using UHTS, it can conduct over 100,000 assays per day. 
There has been an extensive research conducted by major pharmaceutical companies. For instance, the UK’s Medical Research Council Laboratory of Molecular Biology collaborated with AstraZeneca and UCB in August 2017 for speeding the research of drug discovery by offering their academic research along with industrial expertise and infrastructure. However, a lack of skilled labour shall impede the high throughput screening market growth. Furthermore, the processes of target characterization and selection, compound screening, assay development require a lot of time and are expensive to perform, thereby limiting the growth of the market. Moreover, programs like ‘Toxicology in the 21st Century’, a joint venture of the US FDA, EPA and the US NIH, use automated HTS for testing environmental drugs, chemicals and formulation for an extensive toxicological evaluation and in developing pathways that are associated to the disease and can predict the toxicological levels. Such ventures shall pave way for lucrative opportunities to the proliferation of the market.

High Throughput Screening Market

Market Segmentation:

By Products and Services
•    Products
•    Services

By Technology
•    Cell-Based Assays
- Cell Proliferation Assays 
- Cell Viability Assays 
- Cell Cytotoxicity Assays 
- Cell Death Assays 
- Other Cell-Based Assays
•    Lab-on-a-Chips
- PDMS
- Thermopolymers
- Glass
- Silicon
- Paper
•    Ultra high throughput Screening 
- Chip-based Screening 
- Micro-channel Flow Systems 
- Plateless Systems
- Others
•    Label-Free Technology 
- SPR
- ITC
- Others

By Application
•   Drug Discovery
- Medicinal Chemistry
- Biology Services
- Drug Metabolism and Pharmacokinetics (DMPK)
•   Chemical Biology Programs
- Cellular & Biological Simulation
- Disease Modelling 
- Preclinical Drug Development 
- Clinical Trials 
•   Cell & Organ-Based Screening
- Drug Discovery 
- Academic Research 
•   Biochemical Screening
- Blood and Blood –based Products 
- Vaccines and Therapeutics
- Stem Cells 
•   Biological Active Compound Screening 
- Target Identification 
- Primary Screening
- Toxicology 
•   Genomics
- Diagnostic Application
- Precision Medicine
•   Proteomics
- Drug Diagnostics
- Precision Medicine
•   Compound Profiling
- Drug Discovery
- Cancer/Tumor Profiling 
- Toxicology 

By Detection Method
•    Mass Spectrometry 
- Surface-based MALDI-MS
- LASI-MS Imaging 
- Injection-based MS
- Others
•    Chromatography 
- HIC
- HPLC
- SEC
- HPGC
- Others
•    Calorimetry
- Rapid Mass Calorimeter
- ITC
- Nanocalorimetry
- Array Calorimetry
- Others
•    X-ray Diffraction
- In situ Crystallization 
- In meso Crystallization 
- Crystal X-ray Diffraction 
- Others

By End-User
•    Pharmaceutical and Biotechnology Companies
•    Academic and Government Institutes
•    Contract Research Organizations (CRO)
•    Others 
   

By Region
•    North America
•    Europe
•    Asia-Pacific
•    Latin America
•    Middle East and Africa

The market is classified into products and services, technology, application, end user and region. The products and services segment is fragmented into reagents and assay kits, instruments, software and services. The reagents and assay kits segment held the largest high throughput screening market share and this can be credited to an increased used of assay kits and reactors in HTS method, growing occurrences of chronic diseases, increase in the number of research and development activities by pharmaceutical companies, surging assistance from government through massive funding for research in the life sciences sector. However, the software segment is predicted to showcase significant growth during the forecasted timeframe, and this is due to the soaring automation of HTS and the ease of availability of software tools required for data management. 
The technology segment is divided into cell-based assay which is further divided into 2D cell culture and 3D cell culture, lab-on-a-chip, ultra-high throughput screening, bioinformatics and label-free technology. The label-free technology is predicted to record the highest growth during the forecasted timeframe, and this is primarily due to advancements that have improved the throughput, cost, sensitivity and data analysis level. Using assays that are biologically relevant is the new high throughput screening market trend which shall provide growth opportunities for the market. The end user segment is fragmented into CROs, academic and government institutes, pharmaceutical and biotech companies and other end users. The pharmaceutical and biotech companies are expected to lead the market, and this is due to the in-depth usage of HTS technology in these companies for application related to drug discovery.

Regional Analysis:

The North America region is anticipated to dominate the market owing to a rise in the research and development expenditure provided by the pharma and biotech companies and the increased acceptance of HTS in the region. The Asia Pacific region, however, is poised to showcase substantial growth during the forecast period and this can be credited to a soaring expenditure on research and development, increased private-public collaborations and increased export of services offering drug discovery. 

Competitive Landscape:                            

Some of the key market players are Thermo Fisher Scientific, Agilent Technologies Inc., Danaher , PerkinElmer Inc., Tecan Group Ltd., Axxam S.p.A, Bio-Rad Laboratories Inc, Merck Group KGaA, Hamilton Company, Corning Incorporated, Biotek Instruments Inc., Aurora Biomed Inc.

FutureWise Key Takeaways:

•    Growth prospects
•    SWOT analysis 
•    Key market trends 
•    Key data-points affecting market growth

Objectives of the Study:

•    To provide with an exhaustive analysis on the global high throughput screening market by products and services, by technology, by application, by detection method, by end user and by region
•    To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
•    To evaluate and forecast micro-markets and the overall market 
•    To predict the market size, in key regions (along with countries)— North America, Europe, Asia Pacific, Latin America and Middle East and Africa
•    To record, evaluate and analyze competitive landscape mapping- product launches, technological advancements, mergers and expansions  

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