Overview


According to FutureWise analysis the market for immune checkpoint inhibitors in 2023 is US$ 47.22 billion, and is expected to reach US$ 158.26 billion by 2031 at a CAGR of 16.32%.

Immune checkpoint inhibitors are drugs used in advanced-stage cancers. These drugs work on the immunity of the body and the mechanism is to develop the patient’s body immunity to recognise, fight and annihilate the disease-causing bacteria or virus. Unlike other therapies, instead of attacking the tumour, this trains the body and it’s immunity to fight and protect the body from ailments. With the growing incidences of cancer due to the deteriorating environment, drastic climate changes, and rise in the number of smokers, the global immune checkpoint inhibitors market is projected to grow unboundedly during the forecast period. 

People are becoming increasingly aware due to the constant efforts taken by the government and other organisations, this is contributing to the growth of the market. Constant developments and research undertaken by the firms in the market to find new, efficient and improved cures have helped them to soar in terms of revenue. FDA has also approved numerous drugs and several combinations thus leading to other firms entering the market to explore it’s potential.

North America is the largest market globally for immune checkpoint inhibitors. Technological advancements and early diagnosis aid the growth of the market. The Asia Pacific is expected to witness significant growth in the global immune checkpoint inhibitors market and is speculated to grow at a healthy CAGR. 

Firms having a significant share in the global immune checkpoint inhibitors market are AstraZeneca, Bristol-Myers Squibb, Roche Holdings AG, Novartis AG, Pfizer, and Sanofi, among others. Novartis AG, Sanofi and Incyte have their immune checkpoint inhibitor drugs awaiting approvals and thus are expected to expand the reach of the market. The firms operating in the immune checkpoint inhibitors market follow a strategy of entering into collaboration and agreement with other companies for better geographical reach and expansion of services and a larger pool of services. For instance, Bristol-Myer Squibb, an American pharmaceutical company, and Ono Pharmaceuticals, the largest pharmaceutical company in Japan, have a distribution agreement where Ono will hold the rights to distribution on Japan, Taiwan and South Korea.  While,  Bristol-Myer Squibb was provided with an exclusive license by ONO for the development and commercialization of ONO-4578, ONO’s selective Prostaglandin E2 (PGE2) receptor 4 (EP4) antagonist. This helps increase the geographical reach of both the firms as well as their services. Moreover, firms holding major market share are also eyeing potential markets emerging in developing countries such as KSA and South Africa by seeking FDA approvals to their products in these markets.

  • AstraZeneca Plc.
  • Bristol-Myers Squibb Company
  • Eli Lilly and Company (ARMO BioSciences)
  • Fortress Biotech, Inc. (Checkpoint Therapeutics, Inc.)
  • F. Hoffmann-La Roche Ltd. (Genentech, Inc.)
  • Immutep Limited
  • MerckCo., Inc.
  • Merck KGaA (EMD Serono, Inc.)
  • Novartis AG
  • Pfizer Inc.

(Note: The list of the major players will be updated with the latest market scenario and trends)

By Drug Class

  • PD-1
  • PD-L1
  • CTLA-4

By Therapeutic Application 

  • Lung Cancer
  • Melanoma
  • Urothelial Carcinoma
  • Squamous Cell Carcinoma
  • Blood Cancer
  • Other Cancers

By Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies

By Region

  • Europe 
  • North America 
  • APAC 
  • Latin America
  • Rest of World
  • Tier 1 players- established companies in the market with a major market share
  • Tier 2 players
  • Emerging players which are growing rapidly
  • New Entrants
  • Growth prospects 
  • SWOT analysis
  • Key trends
  • Key data points affecting market growth 
  • To provide an exhaustive analysis on the Immune Checkpoint Inhibitors Market By Drug Class, By Therapeutic Application, By Distribution Channel, and By Region
  • To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
  • To evaluate and forecast micro-markets and the overall market 
  • To predict the market size, in key regions (along with countries)—North America, Europe, Asia Pacific, Latin America, and the Middle East.
  • To record evaluate and competitive landscape mapping- product launches, technological advancements, mergers and expansions
  • Profiling of companies to evaluate their market shares, strategies, financials and core competencies 
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Table of Contents


  • 1.   Market Introduction
    •   1. Objectives of the Study
        2. Market Definition
        3. Market Scope
         3.1. Years Considered for the Study
         3.2. Market Covered
        4. Currency
        5. Limitations
        6. Stakeholders
  • 2.   Research Methodology
    •   1. Research Data
         1.1. Secondary Data
          1.1.1. Key Data from Secondary Sources
         1.2. Primary Data
          1.2.1. Key Data from Primary Sources
        2. Market Size Estimation
        3. Market Breakdown and Data Triangulation
        4. Assumptions for the Study
  • 3.   Executive Summary
    •   1. Market Outlook
        2. Segment Outlook
        3. Competitive Insights
  • 4.  Immune Checkpoint Inhibitors Market Variables, Trends and Scope
    •   1. Market Lineage Outlook
        2. Penetration and Growth Prospect Mapping
        3. Industry Value Chain Analysis
        4. Cost Analysis Breakdown
        5. Technology Overview
        6. Regulatory Framework
         6.1. Reimbursement Framework
         6.2. Standards and Compliances

  • 5.  Immune Checkpoint Inhibitors Market Overview
    •   1. Market Dynamics
         1.1. Market Driver Analysis
          1.1.1. Increasing focus of Immune Checkpoint Inhibitors Companies on Brand Protection
          1.1.2. Untapped Opportunities in Emerging Regions
         1.2. Market Restraint Analysis
          1.2.1. High Cost Associated with Implementation of Predictive Analysis
         1.3. Industry Challenges
          1.3.1. Presence of Ambiguous Regulatory Framework

  • 6.  Immune Checkpoint Inhibitors Market Analysis Tools
    •   1. Industry Analysis - Porter’s
         1.1. Supplier Power
         1.2. Buyer Power
         1.3. Substitution Threat
         1.4. Threat from New Entrants
         1.5. Competitive Rivalry
        2. Pestel Analysis
         2.1. Political Landscape
         2.2. Environmental Landscape
         2.3. Social Landscape
         2.4. Technology Landscape
         2.5. Legal Landscape
        3. Major Deals And Strategic Alliances Analysis
         3.1. Joint Ventures
         3.2. Mergers and Acquisitions
         3.3. Licensing and Partnership
         3.4. Technology Collaborations
         3.5. Strategic Divestments
        4. Market Entry Strategies
        5. Case Studies

  • 7.  Immune Checkpoint Inhibitors Market, By Drug Class Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. PD-1
        2. PD-L1
        3. CTLA-4

  • 8.   Immune Checkpoint Inhibitors Market, By Therapeutic Application Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Lung Cancer
        2. Melanoma
        3. Urothelial Carcinoma
        4. Squamous Cell Carcinoma
        5. Blood Cancer
        6. Other Cancers

  • 9.  Immune Checkpoint Inhibitors Market, By Distribution Channel Historical Analysis and Forecast 2023-2031 (USD Million)
    •   1. Hospital Pharmacies
        2. Retail Pharmacies

  • 10.   North America Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. U.S.A
         2.2. Canada
         2.3. Mexico
        3. Market Size (USD Million) Forecast for North America 2023-2031

  • 11.   Latin America Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Regional Market Trends
        3. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         3.1. Brazil
         3.2. Venezuela
         3.3. Argentina
         3.4. Rest of Latin America
        4. Market Size (USD Million) Forecast for Latin America 2023-2031

  • 12.   Europe Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Germany
         2.2. U.K
         2.3. France
         2.4. Italy
         2.5. Spain
         2.6. Russia
         2.7. Poland
         2.8. Switzerland
         2.9. Rest of Western Europe
        3. Market Size (USD Million) Forecast for Europe 2023-2031

  • 13.   Asia Pacific Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Japan
         2.2. China
         2.3. Singapore
         2.4. India
         2.5. Australia and New Zealand
         2.6. ASEAN
         2.7. South Korea
         2.8. Taiwan
         2.9. Rest of Asia Pacific
        3. Market Size (USD Million) Forecast for Asia Pacific 2023-2031

  • 14.   Middle East and Africa Market Analysis 2017-2022 and Forecast 2023-2031 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2017-2022
         2.1. Saudi Arabia
         2.2. UAE
         2.3. South Africa
         2.4. Egypt
        3. Market Size (USD Million) Forecast for MEA 2023-2031

  • 15.   Company Profiles (Competition Dashboard, Competitors Deep Dive, Product Connected Devices and Disease Indication Portfolio, Financial Layouts)
    •   1. AstraZeneca Plc.
         1.1. Company Overview
         1.2. Product Portfolio
         1.3. SWOT Analysis
         1.4. Financial Overview
         1.5. Strategic Overview
        2. Bristol-Myers Squibb Company
         2.1. Company Overview
         2.2. Product Portfolio
         2.3. SWOT Analysis
         2.4. Financial Overview
         2.5. Strategic Overview
        3. Eli Lilly and Company (ARMO BioSciences)
         3.1. Company Overview
         3.2. Product Portfolio
         3.3. SWOT Analysis
         3.4. Financial Overview
         3.5. Strategic Overview
        4. Fortress Biotech, Inc. (Checkpoint Therapeutics, Inc.)
         4.1. Company Overview
         4.2. Product Portfolio
         4.3. SWOT Analysis
         4.4. Financial Overview
         4.5. Strategic Overview
        5. F. Hoffmann-La Roche Ltd. (Genentech, Inc.)
         5.1. Company Overview
         5.2. Product Portfolio
         5.3. SWOT Analysis
         5.4. Financial Overview
         5.5. Strategic Overview
        6. Immutep Limited
         6.1. Company Overview
         6.2. Product Portfolio
         6.3. SWOT Analysis
         6.4. Financial Overview
         6.5. Strategic Overview
        7. Merck & Co., Inc.
         7.1. Company Overview
         7.2. Product Portfolio
         7.3. SWOT Analysis
         7.4. Financial Overview
         7.5. Strategic Overview
        8. Merck KGaA (EMD Serono, Inc.)
         8.1. Company Overview
         8.2. Product Portfolio
         8.3. SWOT Analysis
         8.4. Financial Overview
         8.5. Strategic Overview
        9. Novartis AG
         9.1. Company Overview
         9.2. Product Portfolio
         9.3. SWOT Analysis
         9.4. Financial Overview
         9.5. Strategic Overview
        10. Pfizer Inc.
         10.1. Company Overview
         10.2. Product Portfolio
         10.3. SWOT Analysis
         10.4. Financial Overview
         10.5. Strategic Overview

  • 16.  Impact of COVID-19
    •   1. Positive influence on the healthcare industry
        2. The financial disruption of the manufacturing sector
        3. Impact of COVID-19 on emerging companies
        4. Significant mandates in the regulations initiated by
      healthcare administrations
        5. The overall economic slowdown of the developing and developed nations

  • 17.  Major Deals and Strategic Alliances Analysis
    •   1. Joint ventures
        2. Mergers and acquisitions
        3. Licensing and partnerships
        4. Technology Collaborations
        5. Strategic Divestments
        6. Market Entry Strategies

  • 18.   Key Market Takeaway Points from the Market Analysts at Future Market Analytics
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