- Pfizer Inc.
- Sanofi
- Anika Therapeutics, Inc.
- Ferring B.V.
- Bioventus
- Flexion Therapeutics, Inc.
- Zimmer Biomet Holdings, Inc.
- SEIKAGAKU CORPORATION
- Chugai Pharmaceutical Co., Ltd.
- Allergan Plc.
(Note: The list of the major players will be updated with the latest market scenario and trends)