Overview


The Liquid Biopsy Market focuses on non-invasive tests that detect cancer and other diseases using biomarkers, such as circulating tumor DNA (ctDNA), in blood samples. It is growing due to rising cancer cases, the demand for early detection, advances in genomic technologies, and increased adoption of personalized medicine in oncology.

According to FutureWise analysis, the Liquid Biopsy Market in 2026 is US$11.77 billion, and is expected to reach US$29.45 billion by 2036 at a CAGR of 9.61%. The growing demand for non-invasive diagnostic methods in oncology is boosting the use of liquid biopsies, which enable early cancer detection and real-time treatment monitoring. Advances in circulating tumor DNA (ctDNA), exosome analysis, and next-generation sequencing (NGS) are enhancing the accuracy and application of these methods across different cancer types.

Growth Drivers:

  • Rising global prevalence of cancer
  • Growing demand for non-invasive diagnostic techniques
  • Increasing adoption of personalized and precision medicine
  • Advancements in next-generation sequencing (NGS) and molecular diagnostics
  • Higher focus on early cancer detection and screening programs

Key Trends:

  • Rising adoption of next-generation sequencing (NGS) and AI-powered analytics
  • Shift toward early cancer detection and screening solutions
  • Increasing use of multi-cancer and pan-cancer assays
  • Growth in companion diagnostics and therapy guidance tools
  • Expansion of liquid biopsy applications beyond oncology (e.g., transplant monitoring, prenatal testing)

Market Segmentation and Key Players:

The Liquid Biopsy Market is segmented by product into assay kits, instruments, and services; by biomarker type into circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), cell-free DNA (cfDNA), extracellular vesicles (EVs), and others; by clinical application including early cancer screening, therapy selection, treatment monitoring, and recurrence monitoring; by application into oncology (lung, breast, colorectal, prostate, and other cancers) and non-oncology uses; and by end user such as hospitals, reference laboratories, and academic research centers across major regions. Comprehensive segmentation details are provided in the Segmentation section below.

Major companies operating in the Liquid Biopsy Market include Biocept Inc., Qiagen N.V., and Roche Diagnostics.

Research Methodology:

The Liquid Biopsy Market report by FutureWise Research is developed using a combination of secondary research (industry reports, company filings, databases, and publications) and primary research (interviews with industry experts and key stakeholders). The methodology includes data triangulation, market sizing through quantitative analysis, and forecasting based on current trends, drivers, challenges, and competitive landscape assessment to ensure accurate and reliable market insights.

  • Biocept Inc.
  • Qiagen N.V.
  • Roche Diagnostics.
  • Bio-Rad Laboratories, Inc.
  • Myriad Genetics, Inc.
  • Menarini-Silicon Biosystems.
  • Trovagene Inc.
  • Guardant Health, Inc.
  • Mdxhealth SA.
  • Genomic Health Inc.

Recent developments by key players in Liquid Biopsy Market:

Roche Diagnostics

FDA Approval for ctDNA Test: In June 2025, Roche Diagnostics received FDA approval for a liquid biopsy test based on circulating tumor DNA (ctDNA). This test is designed to aid in therapy selection for non-small cell lung cancer. This approval represents a significant milestone in the clinical use of liquid biopsies for personalized cancer treatment.

Guardant Health

In February 2025, Guardant Health introduced an enhanced cell-free DNA (cfDNA) assay intended to detect early-stage cancers across various indications. This development aims to improve early cancer detection and enable timely intervention.

By Product

  • Assays Kits
  • Instruments
  • Services

By Circulating Biomarker

  • Circulating Tumor Cells (CTCs)
  • Circulating Tumor DNA (ctDNA)
  • Cell-Free DNA (cfDNA)
  • Extracellular Vesicles (EVs)
  • Other Circulating Biomarkers

By Clinical Application

  • Early Cancer Screening
  • Therapy Selection
  • Treatment Monitoring
  • Recurrence Monitoring Orthopedics

By Application

  • Oncology
    • Lung Cancer
    • Breast Cancer
    • Colorectal Cancer
    • Prostate Cancer
    • Melanoma Cancer
    • Other Cancers
  • Non-Cancer Application

By End User

  • Reference Laboratories
  • Hospitals and Physician Laboratories
  • Academic and Research Centers
  • Other End Users

By Region

  • North America
  • Latin America
  • Europe
  • Asia Pacific
  • Rest of the World

Here’s a regional view of where the most progress is happening:

North America leads the Liquid Biopsy Market thanks to its advanced healthcare infrastructure and strong research initiatives. In the United States, the adoption of liquid biopsy technologies for early cancer detection and personalized medicine is rapidly increasing.

Asia-Pacific is becoming a rapidly growing region due to the increasing prevalence of cancer, enhancements in healthcare infrastructure, greater government initiatives, and heightened awareness of non-invasive diagnostic options.

  • Tier 1 players- established companies in the market with a major market share
  • Tier 2 players
  • Emerging players which are growing rapidly
  • New Entrants
     

  • Growth prospects
  • SWOT analysis
  • Key trends Key
  • data-points affecting market growth

  • To provide with an exhaustive analysis on the global Liquid Biopsy Market by product, by circulating biomarker, by clinical application, by application, by end user and by region
  • To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
  • To evaluate and forecast micro-markets and the overall market
  • To predict the market size, in key regions (along with countries)—North America, Europe, Asia Pacific, Latin America, and the Middle East
  • To record evaluate and competitive landscape mapping- product launches, technological advancements, mergers and expansions
  • Profiling of companies to evaluate their market shares, strategies, financials and core competencies

  • We have a flexible delivery model and you can suggest changes in the scope/table of content as per your requirement
  • The customization Mobility Care offered are free of charge with purchase of any license of the report
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Table of Contents


  • 1.   Market Introduction
    •   1. Objectives of the Study
        2. Market Definition
        3. Market Scope
         3.1. Years Considered for the Study
         3.2. Market Covered
        4. Currency
        5. Limitations
        6. Stakeholders
  • 2.   Research Methodology
    •   1. Research Data
         1.1. Secondary Data
          1.1.1. Key Data from Secondary Sources
         1.2. Primary Data
          1.2.1. Key Data from Primary Sources
        2. Market Size Estimation
        3. Market Breakdown and Data Triangulation
        4. Assumptions for the Study
  • 3.   Executive Summary
    •   1. Market Outlook
        2. Segment Outlook
        3. Competitive Insights
  • 4.   Global Liquid Biopsy Market Variables, Trends and Scope
    •   1. Market Lineage Outlook
        2. Penetration and Growth Prospect Mapping
        3. Industry Value Chain Analysis
        4. Cost Analysis Breakdown
        5. Technology Overview
        6. Regulatory Framework
         6.1. Reimbursement Framework
         6.2. Standards and Compliances

  • 5.   Global Liquid Biopsy Market Overview
    •   1. Market Dynamics
         1.1. Market Driver Analysis
          1.1.1. Increasing focus on Brand Protection
          1.1.2. Untapped Opportunities in Emerging Regions
         1.2. Market Restraint Analysis
         1.3. Industry Challenges
          1.3.1. Presence of Ambiguous Regulatory Framework
  • 6.   Global Liquid Biopsy Market Analysis Tools
    •   1. Industry Analysis - Porter’s
         1.1. Supplier Power
         1.2. Buyer Power
         1.3. Substitution Threat
         1.4. Threat from New Entrants
         1.5. Competitive Rivalry
        2. Pestel Analysis
         2.1. Political Landscape
         2.2. Environmental Landscape
         2.3. Social Landscape
         2.4. Technology Landscape
         2.5. Legal Landscape
        3. Major Deals And Strategic Alliances Analysis
         3.1. Joint Ventures
         3.2. Mergers and Acquisitions
         3.3. Licensing and Partnership
         3.4. Technology Collaborations
         3.5. Strategic Divestments
        4. Market Entry Strategies
        5. Case Studies
  • 7.   Global Liquid Biopsy Market, By Product Historical Analysis and Forecast 2026-2036 (USD Million)
    •   1. Assays Kits
        2. Instruments
        3. Services

  • 8.   Global Liquid Biopsy Market, By Circulating Biomarker Historical Analysis and Forecast 2026-2036 (USD Million)
    •   1. Circulating Tumor Cells (CTCs)
        2. Circulating Tumor DNA (ctDNA)
        3. Cell-Free DNA (cfDNA)
        4. Extracellular Vesicles (EVs)
        5. Other Circulating Biomarkers

  • 9.   Global Liquid Biopsy Market, By Clinical Application Historical Analysis and Forecast 2026-2036 (USD Million)
    •   1. Early Cancer Screening
        2. Therapy Selection
        3. Treatment Monitoring
        4. Recurrence Monitoring Orthopedics

  • 10.   Global Liquid Biopsy Market, By Application Historical Analysis and Forecast 2026-2036 (USD Million)
    •   1. Oncology
         1.1. Lung Cancer
         1.2. Breast Cancer
         1.3. Colorectal Cancer
         1.4. Prostate Cancer
         1.5. Melanoma Cancer
         1.6. Other Cancers
        2. Non-Cancer Application

  • 11.   Global Liquid Biopsy Market, By End User Historical Analysis and Forecast 2026-2036 (USD Million)
    •   1. Reference Laboratories
        2. Hospitals and Physician Laboratories
        3. Academic and Research Centers
        4. Other End Users

  • 12.   North America Liquid Biopsy Market Analysis 2019-2025 and Forecast 2026-2036 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2019-2025
         2.1. U.S.A
         2.2. Canada
         2.3. Mexico
        3. Market Size (USD Million) Forecast for North America 2026-2036

  • 13.   Latin America Liquid Biopsy Market Analysis 2019-2025 and Forecast 2026-2036 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2019-2025
         2.1. Brazil
         2.2. Venezuela
         2.3. Argentina
         2.4. Rest of Latin America
        3. Market Size (USD Million) Forecast for Latin America 2026-2036

  • 14.   Europe Liquid Biopsy Market Analysis 2019-2025 and Forecast 2026-2036 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2019-2025
         2.1. Germany
         2.2. U.K
         2.3. France
         2.4. Italy
         2.5. Spain
         2.6. Russia
         2.7. Poland
         2.8. Switzerland
         2.9. Rest of Western Europe
        3. Market Size (USD Million) Forecast for Europe 2026-2036

  • 15.  Asia Pacific Liquid Biopsy Market Analysis 2019-2025 and Forecast 2026-2036 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2019-2025
         2.1. Japan
         2.2. China
         2.3. Singapore
         2.4. India
         2.5. Australia and New Zealand
         2.6. ASEAN
         2.7. South Korea
         2.8. Rest of Asia Pacific
        3. Market Size (USD Million) Forecast for Asia Pacific 2026-2036

  • 16.  Middle East and Africa Liquid Biopsy Market Analysis 2019-2025 and Forecast 2026-2036 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2019-2025
         2.1. GCC
         2.2. Israel
         2.3. South Africa
         2.4. Rest of MEA
        3. Market Size (USD Million) Forecast for MEA 2026-2036

  • 17.  Market Share Analysis and Competitive Landscape
    •   1. Global Landscape - Key Players, Revenue and Presence
        2. Global Share Analysis - Key Players (Tier 1, Tier 2, Tier 3)
        3. Global Emerging Companies
        4. North America - Market Share Analysis and Key Regional Players
        5. Europe - Market Share Analysis and Key Regional Players
        6. Asia Pacific - Market Share Analysis and Key Regional Players
        7. Global Key Player - Growth Matrix

  • 18.   Company Profiles (Competition Dashboard, Competitors Deep Dive, Product Type and Technology Portfolio, Financial Layouts)
    •   1. Biocept, Inc
         1.1. Company Overview
         1.2. Product Portfolio
         1.3. SWOT Analysis
         1.4. Financial Overview
         1.5. Strategic Overview
        2. Qiagen N.V.
         2.1. Company Overview
         2.2. Product Portfolio
         2.3. SWOT Analysis
         2.4. Financial Overview
         2.5. Strategic Overview
        3. Roche Diagnostics
         3.1. Company Overview
         3.2. Product Portfolio
         3.3. SWOT Analysis
         3.4. Financial Overview
         3.5. Strategic Overview
        4. Bio-Rad Laboratories, Inc.
         4.1. Company Overview
         4.2. Product Portfolio
         4.3. SWOT Analysis
         4.4. Financial Overview
         4.5. Strategic Overview
        5. Myriad Genetics, Inc
         5.1. Company Overview
         5.2. Product Portfolio
         5.3. SWOT Analysis
         5.4. Financial Overview
         5.5. Strategic Overview
        6. Menarini-Silicon Biosystems
         6.1. Company Overview
         6.2. Product Portfolio
         6.3. SWOT Analysis
         6.4. Financial Overview
         6.5. Strategic Overview
        7. Trovagene, Inc.
         7.1. Company Overview
         7.2. Product Portfolio
         7.3. SWOT Analysis
         7.4. Financial Overview
         7.5. Strategic Overview
        8. Guardant Health, Inc.
         8.1. Company Overview
         8.2. Product Portfolio
         8.3. SWOT Analysis
         8.4. Financial Overview
         8.5. Strategic Overview
        9. Mdxhealth SA
         9.1. Company Overview
         9.2. Product Portfolio
         9.3. SWOT Analysis
         9.4. Financial Overview
         9.5. Strategic Overview
        10. Genomic Health, Inc.
         10.1. Company Overview
         10.2. Product Portfolio
         10.3. SWOT Analysis
         10.4. Financial Overview
         10.5. Strategic Overview

  • 19.   Pre and Post COVID-19 Impact
    •   1. Positive influence on the healthcare industry
        2. The financial disruption of the manufacturing sector
        3. Impact of COVID-19 on emerging companies
        4. Significant mandates in the healthcare regulations initiated by administrations
        5. The overall economic slowdown of the developing and developed nations
  • 20.   FutureWise SME key takeaway points for Client

FAQ


The liquid biopsy market comprises diagnostic tests that identify cancer-related biomarkers, such as circulating tumor DNA (ctDNA), from bodily fluids like blood, urine, or saliva. These tests facilitate non-invasive detection of cancer, monitoring, and personalized treatment planning.

Key applications include early cancer detection, therapy selection, minimal residual disease (MRD) detection, monitoring treatment responses, and checking for recurrences. It is most commonly utilized in lung, breast, colorectal, and prostate cancers.

Major technologies include next-generation sequencing (NGS), polymerase chain reaction (PCR), digital PCR (dPCR), BEAMing (Beads, Emulsion, Amplification, Magnetics), and microarray-based platforms. These technologies enhance sensitivity and specificity.

Early cancer detection, Monitoring minimal residual disease (MRD), Guiding therapy selection and personalized treatment, Tracking cancer recurrence and treatment response

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