Overview


According to FutureWise analysis the market for moderate-to-severe acne therapeutics in 2026 is US$ 1.59 billion, and is expected to reach US$ 2.68 billion by 2036 at a CAGR of 5.36%. Market growth is fueled by the rising cases of persistent acne, more dermatology consultations, and increased awareness of early intervention. The development of novel biologics, combination therapies, and personalized treatments, along with better access to dermatology care, supports long-term market expansion.

Moderate-to-severe acne therapeutics include a variety of prescription treatments aimed at addressing complex and persistent acne cases that do not adequately respond to over-the-counter options. These conditions often present with widespread inflammatory lesions, nodules, cysts, and are associated with an increased risk of scarring and psychological distress. It is crucial to implement effective therapeutic interventions not only to alleviate symptoms but also to prevent long-term skin damage and enhance the patient's quality of life.

The global prevalence of moderate-to-severe acne is rising among both adolescents and adults. Factors such as hormonal imbalances, genetic predisposition, lifestyle choices, stress, and environmental influences contribute to the severity of the condition. Particularly concerning is adult acne, especially in women, which has become an important clinical issue, driving the demand for focused and sustained treatment options. As understanding of acne as a chronic inflammatory skin disease expands, more patients are seeking professional dermatological care instead of relying solely on self-managed treatments.

Therapeutic options for moderate-to-severe acne include systemic retinoids, oral antibiotics, hormonal therapies, and newer biologic and combination treatments. These therapies aim to reduce sebum production, control bacterial growth, modulate inflammation, and normalize skin cell turnover. Advancements in drug formulations and delivery systems have enhanced treatment efficacy while minimizing side effects, which in turn promotes better patient adherence. Ongoing research into the pathophysiology of acne is paving the way for more personalized and mechanism-driven treatment approaches.

Healthcare trends are also influencing the landscape of moderate-to-severe acne therapeutics. The growth of dermatology clinics, teledermatology services, and improved access to prescription options have made specialized acne care more accessible. Supportive reimbursement policies and increasing investment in dermatology research further bolster market growth. In summary, moderate-to-severe acne therapeutics represent a significant aspect of dermatological care, addressing a condition with both medical and psychosocial ramifications, and playing an essential role in comprehensive skin health management.

FutureWise Market Research has instantiated a report that provides an intricate analysis of Moderate-to-Severe Acne Therapeutics Market trends that shall affect the overall market growth. Furthermore, it includes detailed information on the graph of profitability, SWOT analysis, market share and regional proliferation of this business. Moreover, the report offers insights on the current stature of prominent market players in the competitive landscape analysis of this market.

According to the research study conducted by FutureWise research analysts, the Moderate-to-Severe Acne Therapeutics Market is anticipated to attain substantial growth by the end of the forecast period. The report explains that this business is predicted to register a noteworthy growth rate over the forecast period. This report provides crucial information pertaining to the total valuation that is presently held by this industry and it also lists the segmentation of the market along with the growth opportunities present across this business vertical.

  • Allergan plc
  • Galderma S.A.
  • Johnson & Johnson
  • GlaxoSmithKline plc
  • Pfizer Inc.
  • Sun Pharmaceutical Industries Ltd.
  • Teva Pharmaceutical Industries Ltd.
  • Bausch Health Companies Inc.
  • Mylan N.V.
  • Foamix Pharmaceuticals Ltd.
  • Valeant Pharmaceuticals International Inc.
  • Nestlé Skin Health S.A.
  • F. Hoffmann-La Roche Ltd.
  • AbbVie Inc.
  • Leo Pharma A/S
  • Novan, Inc.
  • Cassiopea SpA
  • Almirall, S.A.
  • Dermira, Inc.
  • BioPharmX Corporation

(Note: The list of the major players will be updated with the latest market scenario and trends)

By Treatment Type

  • Antimicrobials/Antibiotics
  • Systemic isotretinoin
  • Retinoid
  • Hormonal Therapy
  • Combination Therapy
  • Topical retinoid and topical antimicrobial
  • Antibiotics and benzoyl peroxide
  • Photodynamic Therapy
  • Others

By Mode of Administration

  • Oral
  • Topical
  • Others

By Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Drugstores
  • E-Commerce

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

  • Tier 1 players- established companies in the market with a major market share
  • Tier 2 players
  • Emerging players which are growing rapidly
  • New Entrants

  • Growth prospects
  • SWOT analysis
  • Key trends
  • Key data-points affecting market growth

  • To provide with an exhaustive analysis on the Moderate-to-Severe Acne Therapeutics Market By Treatment Type, By Mode of Administration, By Distribution Channel and By Region.
  • To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
  • To evaluate and forecast micro-markets and the overall market
  • To predict the market size, in key regions— North America, Europe, Asia Pacific, Latin America and Middle East and Africa.
  • To record and evaluate competitive landscape mapping- product launches, technological advancements, mergers and expansions

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  • The customization Mobility Care offered are free of charge with purchase of any license of the report
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Table of Contents


  • 1.   Market Introduction
    •   1. Objectives of the Study
        2. Market Definition
        3. Market Scope
         3.1. Years Considered for the Study
         3.2. Market Covered
        4. Currency
        5. Limitations
        6. Stakeholders
  • 2.   Research Methodology
    •   1. Research Data
         1.1. Secondary Data
          1.1.1. Key Data from Secondary Sources
         1.2. Primary Data
          1.2.1. Key Data from Primary Sources
        2. Market Size Estimation
        3. Market Breakdown and Data Triangulation
        4. Assumptions for the Study
  • 3.   Executive Summary
    •   1. Market Outlook
        2. Segment Outlook
        3. Competitive Insights
  • 4.   Global Moderate-to-Severe Acne Therapeutics Market Variables, Trends and Scope
    •   1. Market Lineage Outlook
        2. Penetration and Growth Prospect Mapping
        3. Industry Value Chain Analysis
        4. Cost Analysis Breakdown
        5. Technology Overview
        6. Regulatory Framework
         6.1. Reimbursement Framework
         6.2. Standards and Compliances

  • 5.   Market Overview
    •   1. Market Dynamics
         1.1. Market Driver Analysis
          1.1.1. Increasing focus of Moderate-to-Severe Acne Therapeutics Companies on Brand Protection
          1.1.2. Untapped Opportunities in Emerging Regions
         1.2. Market Restraint Analysis
          1.2.1. High Cost Associated with Implementation of Predictive Analysis
         1.3. Industry Challenges
          1.3.1. Presence of Ambiguous Regulatory Framework
  • 6.   Moderate-to-Severe Acne Therapeutics Market Analysis Tools
    •   1. Industry Analysis - Porter’s
         1.1. Supplier Power
         1.2. Buyer Power
         1.3. Substitution Threat
         1.4. Threat from New Entrants
         1.5. Competitive Rivalry
        2. Pestel Analysis
         2.1. Political Landscape
         2.2. Environmental Landscape
         2.3. Social Landscape
         2.4. Technology Landscape
         2.5. Legal Landscape
        3. Major Deals And Strategic Alliances Analysis
         3.1. Joint Ventures
         3.2. Mergers and Acquisitions
         3.3. Licensing and Partnership
         3.4. Technology Collaborations
         3.5. Strategic Divestments
        4. Market Entry Strategies
        5. Case Studies
  • 7.   Moderate-to-Severe Acne Therapeutics Market, By Treatment Type Historical Analysis and Forecast 2026-2036 (USD Million)
    •   1. Antimicrobials/Antibiotics
        2. Systemic isotretinoin
        3. Retinoid
        4. Hormonal Therapy
        5. Combination Therapy
        6. Topical retinoid and topical antimicrobial
        7. Antibiotics and benzoyl peroxide
        8. Photodynamic Therapy
        9. Others

  • 8.   Global Moderate-to-Severe Acne Therapeutics Market, By Mode of Administration Historical Analysis and Forecast 2026-2036 (USD Million)
    •   1. Oral
        2. Topical
        3. Others

  • 9.   Global Moderate-to-Severe Acne Therapeutics Market, By Distribution Channel Historical Analysis and Forecast 2026-2036 (USD Million)
    •   1. Hospital Pharmacies
        2. Retail Pharmacies
        3. Drugstores
        4. E-Commerce

  • 10.   North America Moderate-to-Severe Acne Therapeutics Market Analysis 2019-2025 and Forecast 2026-2036 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2019-2025
         2.1. U.S.A
         2.2. Canada
         2.3. Mexico
        3. Market Size (USD Million) Forecast for North America 2026-2036

  • 11.   Latin America Moderate-to-Severe Acne Therapeutics Market Analysis 2019-2025 and Forecast 2026-2036 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2019-2025
         2.1. Brazil
         2.2. Venezuela
         2.3. Argentina
         2.4. Rest of Latin America
        3. Market Size (USD Million) Forecast for Latin America 2026-2036

  • 12.   Europe Moderate-to-Severe Acne Therapeutics Market Analysis 2019-2025 and Forecast 2026-2036 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2019-2025
         2.1. Germany
         2.2. U.K
         2.3. France
         2.4. Italy
         2.5. Spain
         2.6. Russia
         2.7. Poland
         2.8. Rest of Europe
        3. Market Size (USD Million) Forecast for Europe 2026-2036

  • 13.   Asia Pacific Moderate-to-Severe Acne Therapeutics Market Analysis 2019-2025 and Forecast 2026-2036 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2019-2025
         2.1. Japan
         2.2. China
         2.3. India
         2.4. Australia and New Zealand
         2.5. ASEAN
         2.6. Rest of Asia Pacific
        3. Market Size (USD Million) Forecast for Asia Pacific 2026-2036

  • 14.   Middle East and Africa Market Analysis 2019-2025 and Forecast 2026-2036 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2019-2025
         2.1. Saudi Arabia
         2.2. UAE
         2.3. South Africa
         2.4. Egypt
        3. Market Size (USD Million) Forecast for MEA 2026-2036

  • 15.   Market Share Analysis and Competitive Landscape
    •   1. Global Landscape - Key Players, Revenue and Presence
        2. Global Share Analysis - Key Players (Tier 1, Tier 2, Tier 3)
        3. Global Emerging Companies
        4. North America - Market Share Analysis and Key Regional Players
        5. Europe - Market Share Analysis and Key Regional Players
        6. Asia Pacific - Market Share Analysis and Key Regional Players
        7. Global Key Player - Growth Matrix
  • 16.   Company Profiles (Competition Dashboard, Competitors Deep Dive, Products Offered and Financial Layouts)
    •   1. Allergan plc.
         1.1. Company Overview
         1.2. Product Portfolio
         1.3. SWOT Analysis
         1.4. Financial Overview
         1.5. Strategic Overview
        2. Galderma Laboratories
         2.1. Company Overview
         2.2. Product Portfolio
         2.3. SWOT Analysis
         2.4. Financial Overview
         2.5. Strategic Overview
        3. Johnson & Johnson
         3.1. Company Overview
         3.2. Product Portfolio
         3.3. SWOT Analysis
         3.4. Financial Overview
         3.5. Strategic Overview
        4. GlaxoSmithKline plc
         4.1. Company Overview
         4.2. Product Portfolio
         4.3. SWOT Analysis
         4.4. Financial Overview
         4.5. Strategic Overview
        5. Pfizer Inc.
         5.1. Company Overview
         5.2. Product Portfolio
         5.3. SWOT Analysis
         5.4. Financial Overview
         5.5. Strategic Overview
            6. Sun Pharmaceutical Industries Ltd.
         6.1. Company Overview
         6.2. Product Portfolio
         6.3. SWOT Analysis
         6.4. Financial Overview
         6.5. Strategic Overview
        7. Teva Pharmaceutical Industries Ltd.
         7.1. Company Overview
         7.2. Product Portfolio
         7.3. SWOT Analysis
         7.4. Financial Overview
         7.5. Strategic Overview
        8. Bausch Health Companies Inc.
         8.1. Company Overview
         8.2. Product Portfolio
         8.3. SWOT Analysis
         8.4. Financial Overview
         8.5. Strategic Overview
        9. Mylan N.V.
         9.1. Company Overview
         9.2. Product Portfolio
         9.3. SWOT Analysis
         9.4. Financial Overview
         9.5. Strategic Overview
        10. Foamix Pharmaceuticals Ltd.
         10.1. Company Overview
         10.2. Product Portfolio
         10.3. SWOT Analysis
         10.4. Financial Overview
         10.5. Strategic Overview
             11. Valeant Pharmaceuticals International Inc.
         11.1. Company Overview
         11.2. Product Portfolio
         11.3. SWOT Analysis
         11.4. Financial Overview
         11.5. Strategic Overview
        12. Nestlé Skin Health S.A.
         12.1. Company Overview
         12.2. Product Portfolio
         12.3. SWOT Analysis
         12.4. Financial Overview
         12.5. Strategic Overview
        13. F. Hoffmann-La Roche Ltd.
         13.1. Company Overview
         13.2. Product Portfolio
         13.3. SWOT Analysis
         13.4. Financial Overview
         13.5. Strategic Overview
        14. AbbVie Inc.
         14.1. Company Overview
         14.2. Product Portfolio
         14.3. SWOT Analysis
         14.4. Financial Overview
         14.5. Strategic Overview
        15. Leo Pharma A/S
         15.1. Company Overview
         15.2. Product Portfolio
         15.3. SWOT Analysis
         15.4. Financial Overview
         5.5. Strategic Overview
            16. Novan, Inc.
         16.1. Company Overview
         16.2. Product Portfolio
         16.3. SWOT Analysis
         16.4. Financial Overview
         16.5. Strategic Overview
        17. Cassiopea SpA
         17.1. Company Overview
         17.2. Product Portfolio
         17.3. SWOT Analysis
         17.4. Financial Overview
         17.5. Strategic Overview
        18. Almirall, S.A.
         18.1. Company Overview
         18.2. Product Portfolio
         18.3. SWOT Analysis
         18.4. Financial Overview
         18.5. Strategic Overview
        19. Dermira, Inc.
         19.1. Company Overview
         19.2. Product Portfolio
         19.3. SWOT Analysis
         19.4. Financial Overview
         19.5. Strategic Overview
        20. BioPharmX Corporation
         20.1. Company Overview
         20.2. Product Portfolio
         20.3. SWOT Analysis
         20.4. Financial Overview
         20.5. Strategic Overview

  • 17.   Pre and Post COVID-19 Impact
    •   1. Positive influence on the healthcare industry
        2. The financial disruption of the manufacturing sector
        3. Impact of COVID-19 on emerging companies
        4. Significant mandates in the healthcare regulations initiated by administrations
        5. The overall economic slowdown of the developing and developed nations
  • 18.   FutureWise SME Key Takeaway Points for Client
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