Overview

Next-Generation Sequencing (NGS) Market Introduction

Next Generation Sequencing (NGS) Sample Preparation Market is anticipated to value over USD 2 billion with a CAGR of over 17% during the forecast period 2020-2027.

Genetics has a large scope in current as well as future research and development. Next generation sequencing (NGS) is a rapidly growing stream in genetic research. It's a parallel sequencing method used to make a whole human genome rapidly. The functional annotations in genetic mutations have become easy with NGS projects.

The NGS sample preparation market has a wide scope currently and in the future also. The recent studies and research on NGS sample preparation is the key factor driving its market growth. The different research organizations get funds for their NGS sample preparation projects by both government and non-government bodies. 

The library preparation and target enrichment get more focus as compared to other product types of the market. To improve the recent traditional diagnostic and treatment methods both play a key role. Target enrichment provides patient compliance in case cancer and tumour treatments as the affected area is targeted directly with reduced harm to other organs.

Drug discovery in NGS sample preparation is a major sector as it gets massive funds and demand in the market. Various biomarkers, DNA fragments can be used for discovering new drugs. Also because of such extensive market demand, the research and diagnostic centres also play a key role in driving market growth.

North America, Europe and Asia Pacific are dominating regions in global NGS sample preparation market. The rising genetic disorders and patient population along with awareness and the research developments, these regions are anticipated to have a large market share.

The key players in the market are Agilent Technologies, Inc. Becton, Dickinson and Company Beckman Coulter (A Subsidiary of Danaher) F. Hoffmann-La Roche AG and so on. Agilent Technologies is anticipated to have a major market share. It has a range of advanced NGS assays for diagnosis of cancer, target enrichment probes, NGS software, NGS quality control, and so on. The availability of these facilities by Agilent Technologies is the key factor driving its market growth in NGS sample preparation across the globe. 

Competitive Landscape:

• Agilent Technologies has provided NGS assays for the detection of somatic cancer and is expected to be the key factos
• Agilent Technologies has a target enrichment probe that targets 151 key genes associated with a wide range of cancers

FutureWise Key Takeaways:

• Drug discovery based on NGS sample preparation
• More focus on target enrichment techniques

Next Generation Sequencing (NGS) Sample Preparation Market Segmentation:

By Product:

• Reagents and consumables market by workflow
• Library preparation and target enrichment market by technology

By Applications:

• Diagnostic applications
• Drug discovery
• Agriculture and animal research
• Other applications

By End User:

• Academic institutes and research centres
• Hospitals and clinics
• Pharmaceutical and biotechnology companies
• Other end users

By Region:

• North America
• Europe
• Asia Pacific
• Rest of the world

Objectives of the Study:

• To provide with an exhaustive analysis on the next generation sequencing (NGS) sample preparation market by products, by applications, by end user and by region.
• To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
• To evaluate and forecast micro-markets and the overall market
• To predict the market size, in key regions (along with countries)— North America, Asia Pacific, Europe and the rest of the world.
• To record evaluate and competitive landscape mapping- product launches, technological advancements, mergers and expansions
• Profiling of companies to evaluate their market shares, strategies, financials and core competencies

Table of Contents

1 Introduction 

1.1 Objectives of the Study 

1.2 Market Definition 

1.3 Market Scope 

        1.3.1 Markets Covered

        1.3.2 Years Considered for the Study

1.4 Currency 

1.5 Limitations 

1.6 Stakeholders 

 

2 Research Methodology

2.1 Research Data 

        2.1.1 Secondary Data

                 2.1.1.1 Key Data From Secondary Sources

        2.1.2 Primary Data

                 2.1.2.1 Breakdown of Primaries

                 2.1.2.2 Key Data From Primary Sources

2.2 Market Size Estimation 

        2.2.1 Product-Based Market Estimation

        2.2.2 End User-Based Market Estimation

2.3 Market Breakdown and Data Triangulation 

2.4 Assumptions for the Study 

3 Executive Summary 

 

4 Premium Insights 

4.1 NGS Sample Preparation: Market Overview 

4.2 NGS Sample Preparation Market Share, By Product, 2020 

4.3 Market, By End User, 2020 vs. 2027 (USD Million) 

4.4 Market, By Application, 2020 vs. 2027 (USD Million) 

4.5 Market, By Region 

 

5 Market Overview 

5.1 Introduction 

5.2 Market Dynamics 

        5.2.1 Drivers

                 5.2.1.1 Advancements in NGS Platforms

                 5.2.1.2 Declining Cost of Sequencing

                 5.2.1.3 Improving Reimbursement Scenario for NGS-Based Diagnostic Tests

        5.2.2 Restraints

                 5.2.2.1 End User Budget Constraints in Developing Countries

        5.2.3 Opportunities

                 5.2.3.1 Initiatives and Funding From Government & Private Bodies for Large-Scale Sequencing Projects

                 5.2.3.2 Increasing Applications of NGS

        5.2.4 Challenges

                 5.2.4.1 Ethical Issues

 

6 NGS Sample Preparation Market, By Product 

6.1 Introduction 

6.2 Reagents & Consumables 

        6.2.1 Rising Adoption of NGS is Supporting the Use of NGS Reagents and Consumables

6.3 NGS Workstations 

        6.3.1 High Throughput and Reduction in Hands-On Time Ensures the Adoption of Workstations in NGS Workflow

 

7 NGS Reagents and Consumables Market, By Workflow 

7.1 Introduction 

7.2 Library Preparation 

        7.2.1 DNA Fragmentation, End Repair, A-Tailing, and Size Selection

                 7.2.1.1 Availability of Products From Various Players Drives the Market for This Segment

        7.2.2 DNA Library Preparation

                 7.2.2.1 Whole Exome Sequencing

                            7.2.2.1.1 Wes is More Cost-Effective and Produces Smaller, More Manageable Datasets for Faster Analysis

                 7.2.2.2 Targeted Sequencing

                            7.2.2.2.1 Targeted Sequencing Helps to Investigate A Variety of Disease Areas, Such as Oncology, Inherited Diseases, Immunology, and Infectious Diseases

                 7.2.2.3 Whole Genome Sequencing

                            7.2.2.3.1 Wgs Enables Clinicians to Understand the Genetic Makeup of Patients and Supports the Diagnosis of Various Diseases

                 7.2.2.4 Others

        7.2.3 RNA Library Preparation

                 7.2.3.1 Gene Expression Analysis

                            7.2.3.1.1 Gene Expression Analysis is Adopted on A Large Scale During Immunology & Stem Cell Research and Neurobiology Studies to Evaluate Cell Differentiation and Development

                 7.2.3.2 Whole Transcriptome Sequencing

                            7.2.3.2.1 Whole Transcriptome Sequencing Helps in Understanding the Functional Elements of the Genome and Underlying Mechanisms of Development and Disease

                 7.2.3.3 Other RNA Applications

7.3 Target Enrichment 

        7.3.1 Targeted Sequencing

                 7.3.1.1 Increased Adoption of Targeted Sequencing in Several Diagnostics to Drive Market Growth

        7.3.2 Whole Exome Sequencing

                 7.3.2.1 Wes is Increasingly Being Used in Clinical Diagnostics for A Variety of Indications to Identify the Underlying Genetic Cause of Disease

        7.3.3 Others

7.4 Quality Control 

        7.4.1 Importance of Quality Control Step in the NGS Workflow & Rising Number of Research Activities Using NGS Technology are the Key Factors Driving Market Growth

 

8 NGS Library Preparation & Target Enrichment Market, By Technology 8.1 Introduction 

8.2 Sequencing By Synthesis (Sbs) 

        8.2.1 Sbs has A Wide Customer Base Owing to Its Well-Established Precision in Sequencing as Well as Its Broad Application Base

8.3 Ion Semiconductor Sequencing 

        8.3.1 Extensive Applications of Ion Semiconductor Sequencing to Drive Market Growth

8.4 Single-Molecule Real-Time Sequencing (Smrt) 

        8.4.1 High Cost of Smrt-Based Platforms to Restrain Market Growth

8.5 Nanopore Sequencing 

        8.5.1 Small Size and Low Equipment Costs to Support the Adoption of Nanopore Sequencing Platforms By Various End Users

8.6 Other Sequencing Technologies 

9 NGS Sample Preparation Market, By Application 

9.1 Introduction 

9.2 Diagnostics 

        9.2.1 Cancer Diagnostics

                 9.2.1.1 Increasing Cancer Patient Population Across the Globe is Driving This Segment

        9.2.2 Infectious Disease Diagnostics

                 9.2.2.1 Lack of Awareness About NGS-Based Diagnosis for Infectious Diseases is Limiting the Growth of This Market

        9.2.3 Reproductive Health Diagnostics

                 9.2.3.1 Increasing Adoption of Nipt to Drive Market Growth

        9.2.4 Other Disease Diagnostic Applications

9.3 Drug Discovery 

        9.3.1 Increasing Use of NGS During Clinical Trials for Drug Discovery and Development to Drive the Adoption NGS Sample Preparation Products

9.4 Agricultural & Animal Research 

        9.4.1 Funding & Support for Animal and Plant Genomics Research to Support the Adoption of NGS Sample Preparation Products

9.5 Other Applications 

 

10 NGS Sample Preparation Market, By End User 

  10.1 Introduction 

  10.2 Academic Institutes & Research Centers 

          10.2.1 Availability of Financial Support for Genomics Research to Support the Growth of This Segment

  10.3 Hospitals & Clinics 

          10.3.1 NGS Technology to Witness Significant Adoption in Disease Diagnosis Owing to Its Advantages Over Conventional Methods

  10.4 Pharmaceutical & Biotechnology Companies 

          10.4.1 Continuous Focus of Pharmaceutical and Biotechnology Companies on Targeted therapies for Precision Medicine to Drive the Growth of This 

End-User Segment

  10.5 Other End Users 

 

11 NGS Sample Preparation Market, By Region 

  11.1 Introduction 

  11.2 North America 

  11.3 US 

          11.3.1 Favorable Regulatory and Reimbursement Scenario for NGS-Based Diagnostics Tests in the Country Drives the Market

  11.4 Canada 

          11.4.1 Favorable Government Funding Scenario in Canada Boost Genomics Research

  11.5 Europe 

  11.6 Germany 

          11.6.1 Strong R&D Base in Germany Supports Market Growth

  11.7 UK 

          11.7.1 Use of NGS-Based Test for Disease Diagnosis Will Drive Market Growth

  11.8 France 

          11.8.1 Support for Genomics Research is A Key Driver of Market Growth

          11.8.2 RoE

  11.9 Asia Pacific 

          11.9.1 China

                     11.9.1.1 NGS Players are Focusing on Strengthening their Presence and OfferiNGS in the Country

          11.9.2 Japan

                     11.9.2.1 Growing Genetic Disorder Incidence in Japan is Driving Market Growth

          11.9.3 India

                     11.9.3.1 Awareness on NGS and Its Advantages is Still Growing in India

          11.9.4 Rest of Asia Pacific

  11.1 Rest of the World 

 

12 Competitive Landscape 

  12.1 Overview 

  12.2 Market Share Analysis

  12.3 Competitive Scenario 

          12.3.1 Product Launches

          12.3.2 Agreements, Partnerships, and Collaborations

          12.3.3 Acquisitions

          12.3.4 Expansions

          12.3.5 Other Developments

  12.4 Vendor Inclusion Criteria 

  12.5 Competitive Leadership Mapping 

          12.5.1 Visionary Leaders

          12.5.2 Innovators

          12.5.3 Dynamic Differentiators

          12.5.4 Emerging Players

 

13 Company Profile 

(Business Overview, Products Offered, Recent Developments, SWOT Analysis, FutureWise Key Takeaways View)*  

  13.1 Agilent Technologies, Inc. 

  13.2 Becton, Dickinson and Company 

  13.3 Beckman Coulter (A Subsidiary of Danaher) 

  13.4 F. Hoffmann-La Roche AG 

  13.5 Illumina, Inc.                              

  13.6 New England Biolabs, Inc. 

  13.7 Nugen Technologies, Inc. (Part of Tecan Trading Ag) 

  13.8 Oxford Gene Technology (Part of Sysmex) 

  13.9 Oxford Nanopore Technologies, Ltd. 

  13.10 Pacific Biosciences of California, Inc. 

  13.11 Perkinelmer, Inc. 

  13.12 QIAGEN N.V. 

  13.13 Raindance Technologies, Inc. (Part of Bio-Rad Laboratories) 

  13.14 Swift Biosciences Inc. 

  13.15 Thermo Fisher Scientific Inc. 

 

14. Research Finding and Conclusion 

15. Appendix 

15.1 Research Methodology 

15.2 Research Data Source

 

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