Overview

Proteomics Market Introduction

Global Proteomics Market is estimated to value over USD 36 billion by 2027 end and register a CAGR of over 12.9% during the forecast period 2020 to 2027. 

The study of the functions and structure of proteins used in drug diagnosis, treatment and discovery of diseases. A proteome is unstable as it is different from cell to cell It is used for the evaluation of the protein production rate, protein interaction, proteins involvement in pathways of the metabolic system, and protein modification. The usage of structural proteomics in identifying the complex protein structure, whereas the functional proteomics is utilized for protein‐protein characteristic interactions in order to demonstrate the functions of the protein.

Proteomics finds in-deep applications in identifying markers for disease diagnosis and drug development and discovery of personalized medicines, which have accelerated the global market in recent years. With growing awareness pertaining to the advantages of personalized medicines, government organizations and companies have increased their expenditure of research and development on developing proteomics.

The global market is predicted to proliferate at a substantial rate over the forecast period, due to personalized medicines getting increasingly popular, soaring expenditure on the research and development and advancements in technology related to proteomics. Moreover, a rise in the availability and awareness of proteomics instruments in developing as well as developed market escalates the market augmentation. Nonetheless, high proteomics component costs and a lack of skilled healthcare professionals in the global proteomics industry hamper the overall market growth. Conversely, profitable opportunities pertaining to the identification of biomarkers and developing mass proteomics based on spectrometry are predicted to offer numerous opportunities for growth to the key players.

The analysis of the global proteomics market size is performed using the component vertical in the report. The component segment accounted for the largest global proteomics market share in 2018, and it is projected to maintain its dominance over the forecast period due to reagents being an integral part of the components of proteomics. The reagents are utilized as a binding material and precursor of chemical reactions during protein structure characterization and analysis. Furthermore, fundamental protocols of proteomics need reagents, which is why this segment is anticipated to occupy the largest market share in the component segment throughout the forecast period.

Key market players are Thermo Fisher Scientific, Inc., Agilent Technologies, Inc., Merck KGaA, Danaher Corporation, Waters Corporation, Bio-Rad Laboratories, Inc., Bruker Corporation, GE Healthcare, Perkinelmer, Inc., Luminex Corporation, Creative Proteomics, Promega Corporation.

Bruker Corporation announced a wide line up of products of mass spectrometry and workflows at the American Society for Mass Spectrometry conference in June 2018. Similarly, ThermoFisher Scientific, Inc. announced iXR Raman Spectrometer in March 2017. This product was manufactured for accurate and rapid structural and chemical analysis. Moreover, Waters Corp. initiated the BioAccord System in January 2019, which is a solution of liquid chromatography-mass spectrometry (LC-MS) that is predicted to extend availability to time-of-flight, high-resolution capabilities of mass spectrometry to more scientists. A considerable rise has been showcased in the collaborations and acquisitions in the global market.

Market Segmentation:

By Instrumentation Technology

• Spectroscopy

- Mass Spectroscopy

- NMR Spectroscopy

- CD Spectroscopy

• Chromatography

- HPLC

- Ion Chromatography

- Affinity Chromatography

- Supercritical Fluid Chromatography

• Electrophoresis

- Gel Electrophoresis

- Capillary Electrophoresis

• Protein Microarrays

- Biochips

• Lab-On-Chips (Microfluidics)
• Protein Chips

- Microarray Instruments

~ Integrated Systems

~ Microarray Scanners

~ Arrayers

• X-ray Crystallography
• Surface Plasmon Resonance
• Protein Fractionation

By Reagent

• Immunoassay Reagents
• Spectroscopy Reagents
• Chromatography Reagents
• Protein Microarray Reagents
• X-Ray Crystallography Reagents
• Electrophoresis Reagents
• Protein Fractionation Reagents

By Service & Software

• Core Proteomics Services

- Protein Identification

- Protein Characterization Services

- Quantitative Proteomics Services

- Protein Purification

- Protein Separation

- Protein Sequencing Services

- Custom Assay Services

• Bioinformation Software & Services

- Bioinformatics Services

- Bioinformatics Tools

- Bioinformatics Databases

By Application

• Clinical Diagnostics
• Drug Discovery
• Other Applications

By Region

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East & Africa

 

FutureWise Key Takeaways:

• Growth prospects
• SWOT analysis
• Key trends
• Key data-points affecting market growth

 

Objectives of the Study:

• To provide with an exhaustive analysis on the global proteomics market by instrumentation technology, by reagent, by service & software, by application and by region
• To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
• To evaluate and forecast micro-markets and the overall market
• To predict the market size, in key regions (along with countries)— North America, Europe, Asia Pacific, Latin America and Middle East & Africa
• To record evaluate and competitive landscape mapping- product launches, technological advancements, mergers and expansions
• Profiling of companies to evaluate their market shares, strategies, financials and core competencies

Table of Contents

1 Introduction 

1.1 Objectives of the Study 

1.2 Market Definition 

1.3 Market Scope 

        1.3.1 Markets Covered

        1.3.2 Years Considered for the Study

1.4 Currency 

1.5 Stakeholders 

1.6 Limitations 

 

2 Research Methodology 

2.1 Research Approach 

        2.1.1 Secondary Research

                 2.1.1.1 Key Data From Secondary Sources

        2.1.2 Primary Research

                 2.1.2.1 Key Data From Primary Sources

                 2.1.2.2 Break Down of Primaries

                 2.1.2.3 Key Industry Insights

2.2 Market Size Estimation 

2.3 Data Triangulation Approach 

2.4 Market Share Estimation 

2.5 Assumptions for the Study 

3 Executive Summary 

 

4 Premium Insights 

4.1 Proteomics: Market Overview 

4.2 Market: Geographic Growth Opportunities 

4.3 Regional Mix: Market 

4.4 Market: Developed vs Developing Markets

 

5 Market Overview 

5.1 Introduction 

5.2 Market Dynamics 

        5.2.1 Market Drivers

                 5.2.1.1 Increasing Demand for Personalized Medicine

                 5.2.1.2 Proteomics Bridges the Gap Between Genomics and Biochemistry

                 5.2.1.3 Increasing Pharmaceutical and Biotechnology R&D Expenditure and Government Funding for Proteomics

                 5.2.1.4 Technological Advancements

        5.2.2 Market Restraints

                 5.2.2.1 High Cost of Instruments

        5.2.3 Market Opportunities

                 5.2.3.1 Growing Prominence of Nanoproteomics—The Convergence of Nanotechnology and Proteomics

                 5.2.3.2 Personalized Proteomics for Precision Health

                 5.2.3.3 High Growth Opportunities in Emerging Countries

        5.2.4 Market Challenges

                 5.2.4.1 Data Management in Proteomics Research

                 5.2.4.2 Low Biomarker Discovery-To-Approval Ratio

 

6 Industry Insights 

6.1 Introduction 

6.2 Industry Trends 

        6.2.1 Integration of Omics Data in Biomedical Sciences

        6.2.2 Growing Focus on Monitoring Post-Translational Modifications

        6.2.3 Increasing Uptake of Label-Free Quantification Techniques

        6.2.4 Integrating Networks and Proteomics

6.3 Unmet Needs Analysis 

        6.3.1 Challenges in Analyzing Low Abundance Proteins

 

7 By Instrumentation Technology 

7.1 Introduction 

7.2 Spectroscopy 

        7.2.1 Mass Spectroscopy

                 7.2.1.1 The Ability of Ms to Identify Small Amounts of Protein From Increasingly Complex Mixtures is A Major Factor Driving Its Use in Proteomics

        7.2.2 NMR Spectroscopy

                 7.2.2.1 NMR Experiments Used to Evaluate the Physical, Chemical, Electronic, and Structural Information of Proteins

        7.2.3 CD Spectroscopy

                 7.2.3.1 CD Spectroscopy is Used to Examine Changes in Secondary Structures of Protein in Response to Environmental Conditions Or Interactions With Other Molecules

7.3 Chromatography 

        7.3.1 HPLC

                 7.3.1.1 The Two Types of HPLC Systems Commonly Available in the Market are Split Flow Systems and Non-Split Flow Systems

        7.3.2 Ion Chromatography

                 7.3.2.1 Ion Chromatography is the Most Commonly Used Chromatographic Method for Separating Proteins, Polypeptides, Nucleic Acids, and Other Charged Molecules

        7.3.3 Affinity Chromatography

                 7.3.3.1 Affinity Chromatography Can Be Used in Two Ways, Either Through the Enrichment of A Specific Class of Proteins Or Depletion of Certain Types of Proteins

        7.3.4 Supercritical Fluid Chromatography

                 7.3.4.1 Sfc and Mass Spectrometry are Used for the Separation and Analysis of Integral Membrane Proteins and Hydrophobic Peptides

7.4 Electrophoresis 

        7.4.1 Gel Electrophoresis

                 7.4.1.1 The Most Common Use of Gel Electrophoresis is the Qualitative Analysis of A Complex Mixture of Proteins

        7.4.2 Capillary Electrophoresis

                 7.4.2.1 Ce Coupled With Ms is Used to Assess the Structure and Identity of Individual Proteins, Including Intact Proteins Over A Wide Molecular Weight Range

7.5 Protein Microarrays 

        7.5.1 Biochips

                 7.5.1.1 Lab-On-Chips (Microfluidics)

                            7.5.1.1.1 Loc is One of the Fastest Growing Areas of Microfabrication and Nanotechnology Development

                 7.5.1.2 Protein Chips

                            7.5.1.2.1 The Automated, Affordable, and Highly Sensitive Solutions Offered By Protein Chips Give Them A Advantage Over Conventional Protein Analysis Tools

        7.5.2 Microarray Instruments

                 7.5.2.1 Integrated Systems

                            7.5.2.1.1 Integrated Systems are Capable of Carrying Out the Entire Procedure of Protein Analysis Without Any Intermediate Steps

                 7.5.2.2 Microarray Scanners

                            7.5.2.2.1 Microarray Scanners Find Applications in the Data Analysis of Proteins, Tissues, and Cells

                 7.5.2.3 Arrayers

                            7.5.2.3.1 Technological Advancements Have Made Microarray Spotters Ideal for Large-Scale Arraying Projects

7.6 X-Ray Crystallography 

        7.6.1 X-Ray Crystallography Helps in the Measurement of the 3D Density Distribution of Electrons in A Crystallized Protein in A Certain Resolution

7.7 Surface Plasmon Resonance 

        7.7.1 Spr Imaging Helps Monitor A Range of Molecular Interactions, Such as Peptide-Protein, Carbohydrate-Protein, Protein-Protein Binding, and Surface Enzyme Kinetics

7.8 Protein Fractionation 

        7.8.1 Protein Fractionation Refers to the Process of Isolating, Identifying, and Characterizing Various Proteins in A Sample of Complex Proteome Mixtures

 

8 By Reagent 

8.1 Introduction 

8.2 Immunoassay Reagents 

        8.2.1 Immunoassay Reagents to Dominate the Market During the Forecast Period

8.3 Spectroscopy Reagents 

        8.3.1 The Use of These Reagents is Increasing With the Rising Adoption of Ms Techniques

8.4 Chromatography Reagents 

        8.4.1 Increasing Demand for Protein Purification is Expected to Drive Market Growth

8.5 Protein Microarray Reagents 

        8.5.1 Use of These Reagents has Increased for Analyzing Protein Interactions

8.6 X-Ray Crystallography Reagents 

        8.6.1 Study of Protein Structural Orientation Forms an Part of Crystallography Study

8.7 Electrophoresis Reagents 

        8.7.1 Increasing Demand for 2d Electrophoresis is Driving the Adoption of These Reagents

8.8 Protein Fractionation Reagents 

        8.8.1 Increasing Protein Separation From Complex Mixtures Makes This One of the Fastest-Growing Segments

9 By Services & Software 

9.1 Introduction 

9.2 Core Proteomics Services 

        9.2.1 Protein Identification Services

                 9.2.1.1 Protein Identification Services to Dominate the Market During the Forecast Period

        9.2.2 Protein Characterization Services

                 9.2.2.1 Characterization Studies Play A Vital Role in Studying Complex Protein Structure, Drug Development, and PTMS

        9.2.3 Quantitative Proteomics Services

                 9.2.3.1 Quantitative Proteomics is Critical for Understanding Protein Expression and Modifications

        9.2.4 Protein Purification Services

                 9.2.4.1 Protein Purification AIDS in Improving the Overall Proteome Analysis and Depends on the Probable Use of the Protein

        9.2.5 Protein Separation Services

                 9.2.5.1 Separation Plays an Important Role in the Characterization of Large-Sized Proteomes

        9.2.6 Protein Sequencing Services

                 9.2.6.1 Identification and Characterization of PTMS is an Important Area of Research That Needs Protein Sequencing

        9.2.7 Custom Assay Services

                 9.2.7.1 Assays are Adopted to Improve the Validation Or Consistency of the Protein Analysis Procedures

9.3 Bioinformatics Software & Services 

        9.3.1 Bioinformatics Services

                 9.3.1.1 Bioinformatics Services are Set to Dominate the Market During the Forecast Period

        9.3.2 Bioinformatics Tools

                 9.3.2.1 Need for Data Management and Quality Enhancement of Results Obtained Makes Tools an Imperative Part of Proteomics

        9.3.3 Bioinformatics Databases

                 9.3.3.1 Databases Majorly Contribute to Storing Proteomics Data Along With Integrating Other Omics Databases

 

10 By Application 

  10.1 Introduction 

  10.2 Clinical Diagnostics 

          10.2.1 Clinical Diagnostics is the Largest Application Segment of the Market

  10.3 Drug Discovery 

          10.3.1 Drug Discovery Applications to Register the Highest Growth in the Forecast Period

  10.4 Other Applications 

 

11 Proteomics Market, By Region 

  11.1 Introduction 

  11.2 North America 

          11.2.1 US

                     11.2.1.1 US Dominates the North American Market

          11.2.2 Canada

                     11.2.2.1 Strong Infrastructure and Availability of Funding for Biomedical Research Will Support Market Growth

  11.3 Europe 

          11.3.1 Germany

                     11.3.1.1 Germany Holds the Largest Share of the European Market

          11.3.2 UK

                     11.3.2.1 The UK has Seen A Surge in the Prevalence of Cancer and Neurological Disorders

          11.3.3 France

                     11.3.3.1 Proteomics Research in France is Strongly Supported By the Government

          11.3.4 Switzerland

                     11.3.4.1 Market Growth is Primarily Driven By the Well-Established Pharmaceutical & Biotechnology Industry in the Country

          11.3.5 Italy

                     11.3.5.1 Growth in This Market is Mainly Driven By Increasing Life Science R&D in the Country, Funded By Both Public and Private Organizations

          11.3.6 Spain

                     11.3.6.1 Spain has A Well-Established Network of Research Centers, Universities, and Hospitals, Which Form an Ideal Environment for Translational Medicine Research

          11.3.7 Rest of Europe

  11.4 Asia Pacific 

          11.4.1 China

                     11.4.1.1 Growth in R&D to Enhance the Technological Capabilities in the Country, Thereby Driving the Demand for High-Quality Research Tools

          11.4.2 Japan

                     11.4.2.1 Large Number of Research Initiatives Towards the Development of Precision Medicine Supporting Market Growth in Japan

          11.4.3 India

                     11.4.3.1 Increasing Pharma R&D and Government Funding in the Biotechnology Industry are the Major Factors Driving Market Growth in India

          11.4.4 Australia

                     11.4.4.1 The Increasing Focus of the Healthcare System on Precision Medicine to Offer Significant Growth Opportunities in Australia

          11.4.5 Rest of Asia Pacific

  11.5 Latin America 

          11.5.1 Brazil

                     11.5.1.1 Research Being Undertaken in the Fields of Neuroscience, Inflammatory Diseases, and Drug Discovery, Among Other Fields to Drive Market Growth in Brazil

          11.5.2 Mexico

                     11.5.2.1 Strong Pharmaceutical Industry in the Country to Provide Significant Growth Opportunities in Mexico

          11.5.3 Rest of Latin America

  11.6 Middle East & Africa 

          11.6.1 Increasing Partnerships Among Global Players With Government Organizations in the Region to Support Growth of Proteomics Research in the Middle East and Africa

 

12 Competitive Landscape

  12.1 Overview 

  12.2 Market Share Analysis 

  12.3 Competitive Leadership Mapping 

          12.3.1 Visionary Leaders

          12.3.2 Innovators

          12.3.3 Dynamic Differentiators

          12.3.4 Emerging Companies

  12.4 Competitive Situation and Trends 

          12.4.1 Product & Services Launches

          12.4.2 Expansions

          12.4.3 Acquisitions

          12.4.4 Other Strategies

 

13 Company Profiles 

  13.1 Thermo Fisher Scientific, Inc. 

  13.2 Agilent Technologies, Inc. 

  13.3 Merck KGaA 

  13.4 Danaher Corporation 

  13.5 Waters Corporation 

  13.6 Bio-Rad Laboratories, Inc. 

  13.7 Bruker Corporation 

  13.8 GE Healthcare 

  13.9 Perkinelmer, Inc. 

  13.10 Luminex Corporation 

  13.11 Creative Proteomics 

  13.12 Promega Corporation

 

Chapter 14 Research Finding and Conclusion 

 

Chapter 15  Research Methodology 

 

Chapter 16  Research Data Source   

Tables

Figures