Overview


According to Futurewise analysis, the market for Vitamin B12 API in 2024 was US$390.11 million and is expected to grow at a CAGR of 6.8% by 2032. This growth is driven by rising demand for dietary supplements, increasing awareness of vitamin deficiencies, and expanding applications in pharmaceuticals and functional foods. Additionally, advancements in production technologies and growing health-conscious consumer trends are further boosting market expansion.

The Vitamin B12 market has seen significant growth in 2024 and 2025. This expansion is attributed to a growing awareness of health benefits, innovations in delivery formats, and the global expansion of major companies. Leading firms are concentrating on product innovation, forming strategic partnerships, and entering emerging markets, which has made the market highly competitive and dynamic.

The market for Vitamin B12 API is experiencing steady growth, driven by increasing demand in various sectors, including pharmaceuticals, nutraceuticals, and fortified food products. There is a heightened awareness of vitamin B12 deficiency, particularly among vegan communities and older adults, which is contributing to the rising demand for these vitamins. Furthermore, advancements in fermentation and biosynthesis technologies are enhancing production efficiency and quality. Additionally, the growing regulatory emphasis on health supplements and preventive healthcare is further supporting the expansion of this market.

Vitamin B12, also known as cobalamin, is an essential vitamin that is vital for several critical biological processes within the body. One of its primary functions is to aid in the formation of red blood cells, which are responsible for transporting oxygen throughout the body. Additionally, vitamin B12 is crucial for DNA synthesis, playing a key role in cellular reproduction and overall genetic health.

FutureWise Market Research has released a report that provides an intricate analysis of Vitamin B12 API Market trends that shall affect the overall market growth. Furthermore, it includes detailed information on the profitability graph, SWOT analysis, market share, and regional expansion of this business. Moreover, the report offers insights on the current stature of prominent market players in the competitive landscape analysis of this market.

According to the research study conducted by FutureWise research analysts, the Vitamin B12 API Market is anticipated to attain substantial growth by the end of the forecast period. The report predicts that this business is expected to register a notable growth rate over the forecast period. This report provides crucial information on the total valuation currently held by the industry, as well as a segmentation of the market and an overview of the growth opportunities present across this business vertical.

  • North China Pharmaceutical Group
  • Kingvit
  • Basic Nutrition
  • EuroAPI
  • Rochem International
  • Wockhardt
  • CSPC Pharmaceutical Group Co., Ltd
  • HealthTech BioActives
  • Antibiotice
  • Pharmavit
  • RX pharmachem

(Note: The list of major players will be updated with the latest market scenario and trends)

Recent developments by key players in the Vitamin B12 API Market:

CSPC Pharmaceutical Group:

  • There is a substantial presence in the Asian market, especially in China.
  • Enhancement of manufacturing capabilities for vitamin active pharmaceutical ingredients (APIs).
  • Concentrate on affordable production techniques.

EuroAPI:

Major Investment Initiative

  • €40 Million Investment: EUROAPI announced a significant investment for a more efficient and sustainable Vitamin B12 production process in France

Market Position: EUROAPI is the sole Western API manufacturer of vitamin B12 for the pharmaceutical industry, playing a crucial role in ensuring global vitamin B12 supply

  • EuroAPI has taken significant steps to enhance its production capabilities and commitment to sustainability. In November 2023, the company acquired BianoGMP, which will strengthen its contract development and manufacturing organization (CDMO) services.
  • Additionally, in a move to boost both output and environmental responsibility, EUROAPI invested $25 million in 2023 to install a biomass boiler at its French facility. This investment aims to reduce the company's ecological footprint while increasing production efficiency.

Pharmavit:

Market Presence

  • Specialization: Producing pharmaceutical-grade vitamins requires careful manufacturing processes to ensure high quality and safety. This focus ensures the vitamins meet strict regulatory standards for medicinal use.
  • Operations: We are passionately involved in the production and supply of vitamin B12 API, ensuring that you receive the best quality for your health needs!

By Type

  • Cyanocobalamin
  • Hydroxocobalamin
    • Hydroxocobalamin Chloride
    • Hydroxocobalamin Acetate
    • Hydroxocobalamin Base
  • Others (Methylcobalamin, etc.)

By Form 

  • Powder
  • Liquid

By Grade 

  • Pharmaceutical Grade
  • Food Grade
  • Industrial Grade

By Distribution Channel 

  • Direct Sales
  • Distributors/Wholesalers
  • Online Retailers
  • Pharmacies
  •  Others

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

Here’s a regional view of where the most progress is happening: 

Asia Pacific

  • In 2024, it held the largest share of the Vitamin B12 market, accounting for over half of the global market.
  • Anticipated to emerge as the fastest-growing region, driven by soaring demand from powerhouses such as China, India, and the dynamic nations of Southeast Asia.
  • Growth is driven by increasing cases of diabetic neuropathy, an aging population, and heightened awareness of supplements.
  • The projected compound annual growth rate (CAGR) is expected to be between 7% and 9%, which is higher than that of other regions.

North America

  • Continues to be a significant revenue source, capturing approximately 40% of the overall vitamin API market.
  • A robust pharmaceutical infrastructure and strong consumer demand for supplements drive the growth.
  • Anticipated to grow at a steady pace, the projected CAGR stands at an impressive 5% to 7%. While this growth may be slower compared to the dynamic trends in the Asia Pacific, it showcases a reliable upward trajectory that offers a sense of stability in the market.

  • Tier 1 players- established companies in the market with a major market share
  • Tier 2 players
  • Emerging players which are growing rapidly
  • New Entrants

  • Growth prospects
  • SWOT analysis
  • Key trends
  • Key data-points affecting market growth

  • To provide with an exhaustive analysis on the Vitamin B12 API Market By Type, By Form, By Grade, By Distribution Channel and By Region
  • To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
  • To evaluate and forecast micro-markets and the overall market
  • To predict the market size, in key regions— North America, Europe, Asia Pacific, Latin America and Middle East and Africa.
  • To record and evaluate competitive landscape, mapping- product launches, technological advancements, mergers and expansions

  • We have a flexible delivery model and you can suggest changes in the scope/table of content as per your requirement
  • The customization Mobility Care offered are free of charge with purchase of any license of the report
  • You can directly share your requirements/changes to the current table of content to: sales@futurewiseresearch.com

Table of Contents


  • 1.  Market Introduction
    •   1. Objectives of the Study 
        2. Market Definition 
        3. Market Scope 
           3.1. Years Considered for the Study
           3.2. Market Covered
        4. Currency 
        5. Limitations 
        6. Stakeholders 

  • 2.  Research Methodology
    •   1 Research Data 
           1.1. Secondary Data
              1.1.1. Key Data from Secondary Sources
           1.2 Primary Data
              1.2.1. Key Data from Primary Sources
        3.Market Size Estimation 
        4. Market Breakdown and Data Triangulation 
        5. Assumptions for the Study 

  • 3.  Executive Summary
    •   1. Market Outlook
        2. Segment Outlook
        3. Competitive Insights

  • 4.  Vitamin B12 API Market Variables, Trends & Scope
    •   1. Market Lineage Outlook
        2. Penetration and Growth Prospect Mapping
        3. Industry Value Chain Analysis
        4. Cost Analysis Breakdown
        5. Application Overview
        6. Regulatory Framework
           6.1. Reimbursement Framework
           6.2. Standards and Compliances

  • 5.  Market Overview
    •   1. Market Dynamics
           1.1. Market Driver Analysis
              1.1.1. Increasing focus of Vitamin B12 API Market Companies on Brand Protection
              1.1.2. Untapped Opportunities in Emerging Regions
           1.2. Market Restraint Analysis
              1.2.1. High Cost Associated with Implementation of Predictive Analysis
           1.3. Industry Challenges
              1.3.1. Presence of Ambiguous Regulatory Framework

  • 6.  Vitamin B12 API Market Analysis Tools
    •   1. Industry Analysis - Porter’s
           1.1. Supplier Power
           1.2. Buyer Power
           1.3. Substitution Threat
           1.4. Threat from New Entrants
           1.5. Competitive Rivalry
        2. Pestel Analysis
           2.1. Political Landscape
           2.2. Environmental Landscape
           2.3. Social Landscape
           2.4. Application Landscape
           2.5. Legal Landscape
        3. Major Deals And Strategic Alliances Analysis
           3.1. Joint Ventures
           3.2. Mergers and Acquisitions
           3.3. Licensing and Partnership
           3.4. Application Collaborations
           3.5. Strategic Divestments
        4. Market Entry Strategies
        5. Case Studies

  • 7.  Vitamin B12 API Market, By Type Historical Analysis and Forecast 2025-2033 (USD Million)
    •   1. Cyanocobalamin
         1.1. Hydroxocobalamin
         1.2. Hydroxocobalamin Chloride
         1.3. Hydroxocobalamin Acetate
         1.4. Hydroxocobalamin Base
        2. Others (Methylcobalamin, etc.)

  • 8.  Vitamin B12 API Market, By Form Historical Analysis and Forecast 2025-2033 (USD Million)
    •   1. Powder
        2. Liquid

  • 9.  Vitamin B12 API Market, By Grade Historical Analysis and Forecast 2025-2033 (USD Million)
    •   1. Pharmaceutical Grade
        2. Food Grade
        3. Industrial Grade

  • 10.  Vitamin B12 API Market, By Distribution Channel Historical Analysis and Forecast 2025-2033 (USD Million)
    •   1. Direct Sales
        2. Distributors/Wholesalers
        3. Online Retailers
        4. Pharmacies
        5. Others

  • 11.  North America Vitamin B12 API Market Analysis 2018-2024 and Forecast 2025-2033 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2018-2024
           2.1. U.S.A
           2.2. Canada
           2.3. Mexico
        3. Market Size (USD Million) Forecast for North America 2025-2033

  • 12.  Latin America Vitamin B12 API Market Analysis 2018-2024 and Forecast 2025-2033 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2018-2024
           2.1. Brazil
           2.2. Venezuela
           2.3. Argentina
           2.4. Rest of Latin America
        3. Market Size (USD Million) Forecast for Latin America 2025-2033

  • 13.  Europe Vitamin B12 API Market Analysis 2018-2024 and Forecast 2025-2033 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2018-2024
           2.1. Germany
           2.2. U.K
           2.3. France
           2.4. Italy
           2.5. Spain
           2.6. Russia
           2.7. Poland
           2.8. Rest of Europe
        3. Market Size (USD Million) Forecast for Europe 2025-2033

  • 14.  Asia Pacific Vitamin B12 API Market Analysis 2018-2024 and Forecast 2025-2033 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2018-2024
           2.1. Japan
           2.2. China
           2.3. India
           2.4. Australia and New Zealand
           2.5. ASEAN
           2.6. Rest of Asia Pacific
        3. Market Size (USD Million) Forecast for Asia Pacific 2025-2033  

  • 15.  Middle East and Africa Market Analysis 2018-2024 and Forecast 2025-2033 (USD Million)
    •   1. Introduction
        2. Historical Market Size (USD Million) Analysis By Country, 2018-2024
           2.1. GCC
           2.2. Israel
           2.3. South Africa
           2.4. Rest of MEA
        3. Market Size (USD Million) Forecast for MEA 2025-2033

  • 16.  Market Share Analysis and Competitive Landscape
    •   1. Global Landscape - Key Players, Revenue and Presence
        2. Global Share Analysis - Key Players (Tier 1, Tier 2, Tier 3)
        3. Global Emerging Companies
        4. North America - Market Share Analysis and Key Regional Players
        5. Europe - Market Share Analysis and Key Regional Players
        6. Asia Pacific - Market Share Analysis and Key Regional Players
        7. Global Key Player - Growth Matrix

  • 17.  Company Profiles (Competition Dashboard, Competitors Deep Dive, Solution Types Offered and Financial Layouts)
    •   1. North China Pharmaceutical Group
         1.1. Company Overview
         1.2. Product Portfolio
         1.3. SWOT Analysis
         1.4. Financial Overview
         1.5. Strategic Overview
        2. Kingvit
         2.1. Company Overview
         2.2. Product Portfolio
         2.3. SWOT Analysis
         2.4. Financial Overview
         2.5. Strategic Overview
        3. Basic Nutrition
         3.1. Company Overview
         3.2. Product Portfolio
         3.3. SWOT Analysis
         3.4. Financial Overview
         3.5. Strategic Overview
        4. EuroAPI
         4.1. Company Overview
         4.2. Product Portfolio
         4.3. SWOT Analysis
         4.4. Financial Overview
         4.5. Strategic Overview
        5. Rochem International
         5.1. Company Overview
         5.2. Product Portfolio
         5.3. SWOT Analysis
         5.4. Financial Overview
         5.5. Strategic Overview
        6. Wockhardt
         6.1. Company Overview
         6.2. Product Portfolio
         6.3. SWOT Analysis
         6.4. Financial Overview
         6.5. Strategic Overview
        7. CSPC Pharmaceutical Group Co., Ltd
         7.1. Company Overview
         7.2. Product Portfolio
         7.3. SWOT Analysis
         7.4. Financial Overview
         7.5. Strategic Overview
        8. HealthTech BioActives
         8.1. Company Overview
         8.2. Product Portfolio
         8.3. SWOT Analysis
         8.4. Financial Overview
         8.5. Strategic Overview
        9. Antibiotice
         9.1. Company Overview
         9.2. Product Portfolio
         9.3. SWOT Analysis
         9.4. Financial Overview
         9.5. Strategic Overview
        10. Pharmavit
         10.1. Company Overview
         10.2. Product Portfolio
         10.3. SWOT Analysis
         10.4. Financial Overview
         10.5. Strategic Overview
        11. RX pharmachem
         11.1. Company Overview
         11.2. Product Portfolio
         11.3. SWOT Analysis
         11.4. Financial Overview
         11.5. Strategic Overview

  • 18.  Pre and Post COVID-19 Impact
    •   1. Positive influence on the healthcare industry
        2. The financial disruption of the manufacturing sector
        3. Impact of COVID-19 on emerging companies
        4. Significant mandates in the healthcare regulations initiated by
                  administrations
        5. The overall economic slowdown of the developing and developed nation

  • 19.  FutureWise SME Key Takeaway Points for Client
    •   

FAQ


The Vitamin B12 API Market encompasses the global supply of pharmaceutical-grade Vitamin B12 used in prescription medications, injectable formulations, and nutritional supplements. These ingredients are vital for treating Vitamin B12 deficiency, pernicious anemia, and neurological conditions.

  • Cyanocobalamin - Most common synthetic form, stable and widely used
  • Methylcobalamin - Active form, preferred for neurological applications
  • Adenosylcobalamin - Coenzyme form, used in specialized treatments
  • Hydroxocobalamin - Injectable form, longer-acting in the body
  • Aging Population: There is an increased prevalence of vitamin B12 deficiency among elderly populations.
  • Rising Health Awareness: Increasing awareness of the importance of vitamin B12.
  • Chronic Disease Prevalence: Diabetes and neurological disorders that require vitamin B12 treatment.
  • Preventive Healthcare: "Transition to nutritional supplementation."
  • Pharmaceutical Applications: Increasing the use of prescription medications.
  • Nutraceutical Demand: The growing supplement industry demands high-quality active pharmaceutical ingredients (APIs).
  • Purity Requirements: The content contains over 98% active ingredients.
  • Regulatory Compliance: Obtaining regulatory approvals from the FDA, EMA, and other relevant agencies.
  • Manufacturing Standards: GMP-certified facilities
  • Testing Protocols: Thorough quality control testing.
  • Traceability: Ensure that all supply chain documentation is complete and accurate.
  • Stability: Enhancing shelf life and maintaining potency.

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