Global Protein Crystallization and Crystallography Market is Estimated to Value Over USD 5 Billion by 2029 End

  • 31 Jul 2019
  • Chemicals & Advanced Materials

The Global Protein Crystallization and Crystallography Market is estimated to value over USD 5 billion by 2029 end and is expected to register a CAGR of 10% during the forecast period 2019 to 2029.

The process of protein crystallization and crystallography is widely used for industrial and scientific purposes. Protein crystallization and crystallography develop well-ordered protein crystals that overcomes the fragility of protein molecules which is inherently present in them. Important factors that influence the process are pH value, purity of proteins, protein concentration, additives, precipitation and temperature of the medium.

Factors Influencing the Market Growth


  • The development of innovative technologies primarily influences the protein crystallization and crystallography market
  • A growing need for high resolution protein structure-related information will boost the market further
  • Increasing governmental grants on research and development activities in the pharmaceutical and biotechnological industries will increase the demand of utilizing crystallization and crystallography techniques
  • The advent of advanced technologies like X-ray free electron lasers in protein crystallography and crystallization shall expand the market proliferation


  • A dearth of skilled and experienced personnel to conduct this process shall restrain the market growth
  • The protein crystallization and crystallography is a time-consuming and costly process which can negatively impact the market growth
  • Additionally, this method is limited to a particular type of protein molecules which will restrain the market proliferation significantly

Insights on Global Protein Crystallization and Crystallography Market:

1. By Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Rest of the World

North America dominates the global market owing to the presence of major pharmaceutical and biotechnological companies. Additionally, the research and development activities are soaring in the region resulting into a significant market augmentation.

The European market is projected to showcase significant market growth during the forecast period owing to the increasing acceptance of protein crystallization and crystallography coupled with positive governmental initiatives.

2. By Technology

  • Protein Purification
    • Chromatography
      • Affinity Chromatography
      • Ion Exchange Chromatography
      • High-Pressure Liquid Chromatography (HPLC)
      • Gel-Filtration Chromatography
    • Electrophoresis
      • Gel Electrophoresis
      • Capillary Electrophoresis
    • Others
  • Protein Crystallization
    • Instruments
      • Liquid-handling Systems and Robots
      • Crystallization Plates/Microplates
      • Others
    • Reagents/Consumables
      • Crystallization Screens
      • Others
  • Protein Crystal Mounting
  • NMR Spectroscopy
  • Protein Crystallography
    • X-ray Crystallography
  • SAXS
  • Cryo-Electron Microscopy

Nuclear magnetic resonance (NMR) spectroscopy is used by biochemists to identify proteins and other complex molecules. This process provides a detailed information about the dynamics, structure, chemical environment and reaction state of different protein molecules. NMR spectroscopy has replaced conventional wet chemistry testes like typical chromatography or colour reagents for identifying protein. The only disadvantage that this segment has is it requires a large amount of purified substance which can significantly affect the market augmentation.

3. By End User

  • Pharmaceuticals
  • Biotechnology Companies
  • Governmental Institutions
  • Academic Institutions

The governmental institution segment is projected to showcase a moderate market growth during the forecast period as it is crucial for them to study different protein molecules and understand their functionality for research and development purposes. Additionally, as these institutions are operated by the government, they receive strong financial assistance which boosts the research and development activities thus augmenting the market growth.

Competitive Landscape:

  • Tier 1 players- established companies in the market with a major market share  
  • Tier 2 players 
  • Emerging players which are growing rapidly 
  • New Entrants

Key Market Players:

  • Hampton Research
  •  Molecular Dimensions Ltd.
  • PerkinElmer Inc.
  • GE Healthcare
  • Danaher Corp.
  • Bruker Corp.
  • Agilent Technologies
  • Jena Bioscience
  • Rigaku Corp.

FutureWise Key Takeaways

  • Growth prospects
  • SWOT analysis
  • Key trends
  • Key data-points affecting market growth

Objectives of the Study:

  • To provide with an exhaustive analysis on the global protein crystallization and crystallography market by region, by technology, by end user
  • To cater comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
  • To evaluate and forecast micro-markets and the overall market
  • To predict the market size, in key regions (along with countries)— North America, Europe, Asia Pacific, Latin America and rest of the world
  • To record evaluate and competitive landscape mapping- product launches, technological advancements, mergers and expansions


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