The global protein sequencing market is estimated to be valued at over US$ 4.49 billion by 2033 and is projected to register a CAGR of above 3.69% during the forecast period of 2025-2033.
The key factor driving the growth of the protein sequencing market is the increasing funding for proteomics research and the growing emphasis on developing target-based drugs. Advancements in analytical methods and peptide sequencing have presented a lucrative opportunity for manufacturers. Technological advancements in mass spectrometers are complementing the market growth. The increasing demand for protein biomarkers in the drug development process is also playing a vital role in the expansion of the protein sequencing market size.
The market is bifurcated into product & service, technology, application, end-user, and region. In terms of product and service, protein sequencing services are expected to be the front-runner in the market. The advancement of instruments has led to an increase in launches and the availability of advanced instruments, which has played a vital role in the market's growth. Furthermore, the high cost of sequencing infrastructure and fewer complexities associated with the procedure of protein sequencing is bolstering the market.
Mass spectrometry technology is expected to experience high growth due to its benefits, including the identification of modified proteins and cost efficiency. Prominent players aiming to launch technologically advanced spectrometry instruments are propelling the growth of the protein sequencing market.
The academic institutes and research centers segment is expected to control the market growth. Rising research and development activities, coupled with increased funding from private and public institutions regarding proteomic research, are driving the growth of academic institutes and research, thereby propelling the protein sequencing market.
North America is the global leader of the market. An increase in research and development activities, alongside increased funding from government and private organizations for proteomic research, is boosting the market's presence in the region. Furthermore, a rise in drug development activities and an increasing focus on structure-based drug design are stimulating the market in regions such as the US and Canada. The presence of prominent players in the region is also positively influencing the market.
Global Protein Sequencing Market Segmentation
By Product and Service
- Sample Preparation Products and Services
- Protein Sequencing Products
- Reagents and Consumables
- Instruments
- Mass Spectrometry Instruments
- Edman Degradation Sequencers
- Analysis Products/Software
- Protein Sequencing Services
By Technology
- Edman Degradation
- Mass Spectrometry
By Application
- Biotherapeutics
- Genetic Engineering
- Other Applications
By End User
- Academic Institutes and Research Centers
- Pharmaceutical and Biotechnology Companies
- Other End Users
By Region
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East and Africa
North America is the global leader of the market. An increase in research and development activities, alongside increased funding from government and private organizations for proteomic research, is boosting the market's presence in the region. Furthermore, a rise in drug development activities and an increasing focus on structure-based drug design are stimulating the market in regions such as the US and Canada. The presence of prominent players in the region is also positively influencing the market.
North America leads with approximately USD 0.40 billion in 2023, driven by robust life science infrastructure and R&D capacity.
Europe holds ~USD 0.25 billion, with expanding collaborations and funding.
Asia-Pacific is emerging (~USD 0.15 billion), with rapid biotech development in nations like China, India, and Japan.
South America and MEA are nascent but strategically positioned for future growth. By 2032, projections estimate expansion to USD 1.05B (North America), USD 0.70B (Europe), and USD 0.45B (APAC)
Major players included in the Protein Sequencing Market:
- Agilent Technologies, Inc.
- Bioinformatics Solutions
- Charles River Laboratories
- Proteome Factory
- Rapid Novor Inc.
- Selvita,
- SGS
- Shimadzu Corporation
- Thermo Fisher Scientific Inc.
- Waters
Recent Developments by Leading Companies
Agilent Technologies
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In September 2024, Agilent and GenNext Technologies teamed up to integrate GenNext’s AutoFox Protein Footprinting System with Agilent’s 6560 IM Q-TOF LC/MS to deepen structural biology insights.
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In July 2024, Agilent acquired Sigsense, an AI-driven lab operations platform designed to automate and optimize workflows.
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At the June 2024 American Society for Mass Spectrometry meeting, Agilent unveiled its HES 2.0 ion source, offering attogram-level sensitivity and integrated intelligence.
Thermo Fisher Scientific
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In June 2024, Thermo Fisher introduced its Stellar mass spectrometer, engineered to enhance clinical proteomics research.
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Earlier, in October 2023, it completed acquisition of Olink—bolstering its proteomics capabilities with Olink’s Proximity Extension Assay platform and a vast biomarker library.
Bioinformatics Solutions Inc.
Objectives of the Study:
- To provide an exhaustive analysis on the Protein Sequencing Market By Product and Service, By Technology, By Application, By End User and By Region
- To provide comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
- Evaluate and forecast micro-markets and the overall market
- To predict the market size, in key regions (along with countries)—North America, Europe, Asia Pacific, Latin America the Middle East and Africa
- To record, evaluate, and competitive landscape mapping- product launches, technological advancements, mergers and expansions
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