The global gene expression analysis market is projected to reach a value of over US$ 10 billion by 2033, registering a compound annual growth rate (CAGR) of over 9.1% by 2033.

The increased focus towards the healthcare framework alongside the rapid adoption of the latest advanced technologies in drug development and modern diagnostics is driving the gene expression analysis market growth. Furthermore, the optimization of gene profiling study for the advancement of novel therapeutics due to more efficient time and affordable cost is boosting the market growth. A recent fall in the price of genetic sequencing has allowed more availability of the clinical application, thus propelling the market. The implementation of the Precision Medicine Initiative (PMI) has fueled the deployment of advanced medical tools in the healthcare sector which positively influences the market. The invention of cap analysis of gene expression has played a vital role in overcoming the limitations of microarrays. Cap Analysis of Gene Expression (CAGE) permits in-depth mapping of human recordings. This has led to a frequent enhancement of products and rise in the implementation of novel platforms which play an important role in the escalation of the gene expression analysis market growth.

The gene expression analysis market is bifurcated into by process, by product, by capacity, by technique, by application, and by region. In terms of process, PCR analysis is expected to hold a vast share of the market. Multiple types of research opt for PCR analysis to examine expressions related to multiple microorganisms and genes. Easy integration of PCR analysis with another immunoprecipitation assay such as ChIP-PCR to amend its performance is also anticipated to stimulate the market.

In terms of products, kits & reagents are expected to dominate the market growth. Kits and reagents, when compared to others, are more effective and are available at affordable prices. The introduction of novel and efficient reagents is expected to expand the gene expression analysis market size.

Based on capacity, low to mid plex is expected to show notable growth. Advancements in genetic engineering and stem cell research has enhanced the development of low to mid plex thus inflating the market. Increased research in the field of stem cell therapy, single-cell analysis, cancer genomics, and regenerative therapy is thriving in the market.

Based on application, drug discovery and development is expected to be the front runner of the market owing to increasing preference towards drug response testing for various diseases such as cardiac conditions, rare genetic disorders, and tuberculosis.

Based on the technique, RNA expression is the frontrunner of the market. The rising demand for DNA microarrays and PCR analysis has resulted in the inflation of the market. Besides, the integration of immunoprecipitation assay with these techniques has also positively influenced the market. The emergence of the next-generation sequencing is expected to propagate the market growth.

Emerging Trends:

  • Integration of AI and Machine Learning: The incorporation of artificial intelligence in gene expression analysis enhances data interpretation and predictive analytics, offering deeper insights into gene behavior and disease mechanisms.

  • Single-Cell Analysis Growth: Single-cell gene expression analysis provides unprecedented resolution in studying cellular heterogeneity, crucial for understanding complex biological processes and developing targeted therapies.

  • Multi-Omics Approaches: Combining gene expression data with genomics, epigenomics, proteomics, and metabolomics offers a comprehensive understanding of biological systems, facilitating the discovery of novel biomarkers and therapeutic targets.

Global Gene Expression Analysis Market Segmentation:

By Process

  • Sample Collection
  • Purification
  • cDNA synthesis and conversion
  • PCR Analysis
  • Data analysis and interpretation

By Product

  • Kits and Reagents
  • DNA Chips
  • Others

By Capacity

  • Low- to Mid- Plex
  • High-Plex

By Technique

  • RNA Expression
    • Northern Blotting
    • DNA Microarrays
    • PCR Techniques
    • RNA-Seq
  • Promoter Analysis
    • In vitro Transcription/Nuclear Run-On Assays
    • Gel Shift Assays
    • Chromatin Immunoprecipitation (ChIP)
  • Protein Expression and Posttranslational Modification Analysis
    • Western Blotting
    • 2-D Gel Electrophoresis
    • Immunoassays
    • Mass Spectrometry

By Application

  • Drug Discovery and Development
  • Clinical Diagnostics
  • Biotechnology and Microbiology
  • Others

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

North America dictates the market growth. The presence of developed healthcare infrastructure and prominent players in the region is driving the market. Besides, the increasing government support and demand for precision medicine is also complementing the growth of the market in the region. The increasing prevalence of genetic disorders, alongside the rapid advancement in the biotechnology field, is also playing a vital part in the expansion of the market in the region.

Asia-Pacific region is projected to be a lucrative region owing to the imposition of government policies that favour foreign investments. Countries like Japan, India, and China are allowing the considerable number of prominent players to invest in gene therapy thus propelling the market in the region.

Major players included in the Gene Expression Analysis Market:

  • Thermo Fisher Scientific
  • Illumina, Inc.
  • Agilent Technologies
  • QIAGEN N.V
  • PerkinElmer
  • BGI
  • GE Healthcare
  • Hoffman-La Roche Ltd
  • Bio-Rad Laboratories, Inc. 
  • Pacific Biosciences of California, Inc.

Recent Developments by Key Industry Players

  • Illumina and Broad Institute Collaboration: In August 2024, Illumina partnered with the Broad Institute to develop new gene sequencing kits utilizing CRISPR technology, aiming to scale up gene sequencing volume through PerturbSeq screening. 

  • Bio-Rad Laboratories' New Product Launch: In June 2024, Bio-Rad Laboratories introduced the DDSEQTM single-cell 3'-RNA-seq kit and complementary Omnition V1.1 analysis software for single-cell transcriptome and gene expression studies. 

Objectives of the Study:

  • To provide an exhaustive analysis on the gene Gene Expression Analysis Market By Process, By Product, By Capacity, By Technique, By Application, and By Region
  • To provide comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
  • Evaluate and forecast micro-markets and the overall market
  • To predict the market size, in key regions (along with countries)—North America, Europe, Asia Pacific, Latin America the Middle East, and Africa
  • To record, evaluate,e and competitive landscape mapping- product launches, technological advancements, mergers, and expansions

 

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