The oligonucleotide synthesis market is expected to be valued at over USD 21.07 billion by 2033, with a CAGR of over 17% during the forecast period from 2025 to 2033.
Oligonucleotide synthesis is the process of compounding relatively short fragments of nucleic acid with a defined sequence. It is a vital part of genetic research and has a wide range of applications like diagnosis, tissue engineering, library preparation, DNA sequencing, PCR assays, and so on. Due to the extensive scope of research and development, the oligonucleotide market is growing rapidly.
The inclination towards finding more efficient alternatives to traditional diagnostics and treatments is one of the factors driving the scale-up of the oligonucleotide synthesis market. For the past few years, several genetic diagnostic and clinical measures have boosted the market of oligonucleotide synthesis.
The oligonucleotide synthesizing equipment is expected to hold a large market share as they are the primary preference of end users. The key market players provide a range of synthesizers that add value to the market. Oligonucleotide synthesis is impossible without suitable reagents like linkers, activators, dyes, DNA probes and so on. This is a driving factor for the rise in demand for reagents in the market and is anticipated to hold a large oligonucleotide synthesis market share.
Key Market Drivers
Therapeutic Applications: Synthetic oligonucleotides are being developed as therapeutics to target specific disease-causing genes and proteins. Their ability to bind to specific RNA or DNA molecules allows for precise treatment approaches, surpassing traditional small-molecule drugs in specificity and efficacy.
Molecular Diagnostics: The role of oligonucleotides in molecular diagnostics is expanding, with applications in early disease detection and diagnosis. Synthetic oligonucleotides serve as probes to detect specific DNA or RNA sequences, facilitating the identification of genetic mutations and pathogens.
Advancements in Synthesis Technologies: Innovations in synthesis methods, including solid-phase synthesis, enzymatic synthesis, and microarray synthesis, have improved the efficiency and cost-effectiveness of oligonucleotide production, meeting the growing demand across various sectors.
Global Oligonucleotide Synthesis Market Segmentation:
By Product
- Synthesized Oligonucleotide Product
- Reagents
- Equipment
By Application
- Research
- Diagnostics
- Therapeutics
By Type
- Antisense Oligonucleotide-based Therapies
- RNAi Oligonucleotide-based Therapies
- CpG Oligonucleotide-based Therapies
By Disease Type
- Neurological Disorders
- Infectious Diseases
- Other Diseases
By End User
- Hospitals
- Pharmaceutical & Biotechnology Companies
- Diagnostic Laboratories
- CROs and CMOs
- Academic Research Institutes
By Region
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East & Africa
North America held the largest market share in 2022, driven by the high prevalence of chronic and rare diseases, substantial R&D investments, and the presence of key industry players. The region's focus on precision medicine and the adoption of advanced therapies contribute to its market dominance.
Asia-Pacific is anticipated to experience the fastest growth during the forecast period, attributed to increasing healthcare expenditures, expanding biotechnology sectors, and supportive government initiatives in countries like China and India
Major players included in the Oligonucleotide Synthesis Market:
- Danaher Corporation
- Thermo Fisher Scientific, Inc.
- Merck KGaA
- LGC Limited
- Maravai Life Sciences
- Agilent Technologies, Inc.
- Biogen Inc.
- Sarepta Therapeutics, Inc.
- Eurofins Scientific
- Kaneka Corporation
- Biolytic Lab Performance Inc.
- Microsynth Ag
Agilent Technologies announced a $725 million investment in January 2023 to double its manufacturing capacity for therapeutic nucleic acids at its Frederick, Colorado facility.
Objectives of the Study:
- To provide an exhaustive analysis on the Oligonucleotide Synthesis Market By Product, By Application, By Type, By Disease Type, By End User, and By Region.
- To provide comprehensive information on factors impacting market growth (drivers, restraints, opportunities, and industry-specific restraints)
- To evaluate and forecast micro-markets and the overall market
- To predict the market size, in key regions— North America, Europe, Asia Pacific, Latin America, the Middle East and Africa.
- To record and evaluate competitive landscape mapping- product launches, technological advancements, mergers, and expansions
Get unlimited analyst support and customise this study further to your requirements, contact sales@futurewiseresearch.com